Application of Surface-Enhanced Raman Spectroscopy Combined with Immunoassay for the Detection of Adrenoceptor Agonists

Foods Pub Date : 2024-06-08 DOI:10.3390/foods13121805
Yao Wang, Yubing Jing, Jinbo Cao, Yingying Sun, Kaitong Guo, Xiujin Chen, Zhaozhou Li, Qiaoqiao Shi, Xiaofei Hu
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Abstract

Rapid, sensitive, and accurate detection of adrenoceptor agonists is a significant research topic in the fields of food safety and public health. Immunoassays are among the most widely used methods for detecting adrenoceptor agonists. In recent years, surface-enhanced Raman spectroscopy combined with immunoassay (SERS-IA) has become an effective technique for improving detection sensitivity. This review focuses on the innovation of Raman reporter molecules and substrate materials for the SERS-IA of adrenoceptor agonists. In addition, it also investigates the challenges involved in potentially applying SERS-IA in the detection of adrenoceptor agonists. Overall, this review provides insight into the design and application of SERS-IA for the detection of adrenoceptor agonists, which is critical for animal-derived food safety and public health.
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应用表面增强拉曼光谱与免疫测定相结合检测肾上腺素受体激动剂
快速、灵敏、准确地检测肾上腺素受体激动剂是食品安全和公共卫生领域的一个重要研究课题。免疫测定是检测肾上腺素受体激动剂最广泛使用的方法之一。近年来,表面增强拉曼光谱与免疫测定相结合(SERS-IA)已成为提高检测灵敏度的有效技术。本综述重点介绍了用于肾上腺素受体激动剂 SERS-IA 的拉曼报告分子和底物材料的创新。此外,它还探讨了将 SERS-IA 应用于肾上腺素受体激动剂检测的潜在挑战。总之,本综述深入探讨了用于检测肾上腺素受体激动剂的 SERS-IA 的设计和应用,这对动物源性食品安全和公共卫生至关重要。
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