Influence of heat assisted friction stir processing on the mechanical properties and cell viability in PLA/basalt/graphene nanocomposites

IF 2.4 3区 化学 Q3 POLYMER SCIENCE Iranian Polymer Journal Pub Date : 2024-06-06 DOI:10.1007/s13726-024-01343-4
Arun Nallathambi, Prakash Muniyandi
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Abstract

Polylactic acid (PLA) composites have been widely used in biomedical implants because of biocompatibility and improved mechanical properties. The aim of this study is to produce the polymer nanocomposite with the graphene nanoparticles as a filler through heat-assisted shoulder less friction stir processing (FSP) and to investigate the effect of the process parameter on the microstructural and mechanical characteristics. Rotational speed of 600 rpm is kept constant, tool feed rate of 10, 15 and 20 mm/min, volume fraction of 5%, 10% and 15% of graphene nanopowder and shoulder temperature of 35, 40 and 45 °C are taken as parameters to conduct the FSP. Response surface methodology (RSM) is performed to identify the process parameters which significantly affect the process. Microstructural observations have been conducted to confirm the presence of graphene nanoparticles along the direction of the FSP. In addition, the tensile and microhardness tests have been carried out to analyze the mechanical properties of the prepared samples. The results of methyl thiazol tetrazolium (MTT) assay analysis conducted on human osteoblastic cell line (MG63) show that the sample fabricated with 10% and 15% of graphene nanoparticles is nontoxic and holds a better survivability after a 48 h of study under in vitro culture conditions for tissue in-growth and confirms that this could be applicable for bone implants. The findings of the ANOVA verify that the temperature is the least important factor for producing a composite with better performance, while the volume percentage and feed rate are the most important factors.

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热辅助摩擦搅拌加工对聚乳酸/沥青/石墨烯纳米复合材料机械性能和细胞活力的影响
聚乳酸(PLA)复合材料因其生物相容性和更好的机械性能而被广泛应用于生物医学植入物中。本研究旨在通过热辅助肩式少摩擦搅拌加工(FSP)制备以石墨烯纳米颗粒为填料的聚合物纳米复合材料,并研究工艺参数对微观结构和机械特性的影响。在进行 FSP 时,转速保持恒定为 600 rpm,刀具进给速度分别为 10、15 和 20 mm/min,石墨烯纳米粉体的体积分数分别为 5%、10% 和 15%,肩温分别为 35、40 和 45 °C。采用响应面方法 (RSM) 确定对工艺有重大影响的工艺参数。通过微观结构观察,确认了石墨烯纳米颗粒沿 FSP 方向的存在。此外,还进行了拉伸和显微硬度测试,以分析制备样品的机械性能。在人成骨细胞系(MG63)上进行的甲基噻唑四氮唑(MTT)检测分析结果表明,在体外培养条件下进行 48 小时的组织内生长研究后,含有 10% 和 15% 石墨烯纳米颗粒的样品是无毒的,并具有更好的存活率,这也证实了它可用于骨植入物。方差分析结果证实,温度是生产性能更好的复合材料的最不重要因素,而体积百分比和进料速率则是最重要的因素。
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来源期刊
Iranian Polymer Journal
Iranian Polymer Journal 化学-高分子科学
CiteScore
4.90
自引率
9.70%
发文量
107
审稿时长
2.8 months
期刊介绍: Iranian Polymer Journal, a monthly peer-reviewed international journal, provides a continuous forum for the dissemination of the original research and latest advances made in science and technology of polymers, covering diverse areas of polymer synthesis, characterization, polymer physics, rubber, plastics and composites, processing and engineering, biopolymers, drug delivery systems and natural polymers to meet specific applications. Also contributions from nano-related fields are regarded especially important for its versatility in modern scientific development.
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