Prostatic sarcoidosis mimicking malignancy: A report of rare case with review of literature

Abstract

Sarcoidosis is a systemic granulomatous disorder affecting individuals worldwide. It can affect all organs to a varying extent. Involvement of the prostate gland is extremely unusual with only 18 cases reported yet in literature. We hereby, present such a rare case of a 60-year-old male with severe urinary symptoms and elevated PSA levels upto 5.12 ng/ml. On radiological evaluation, the lesion was reported as suspicious of prostate cancer (PIRAD-4). The patient underwent prostatic biopsy, which revealed a non-caseating granulomatous lesion destroying the prostate parenchyma. With the history of previous diagnosis of pulmonary sarcoidosis, the diagnosis of prostatic sarcoidosis was rendered.