A hot-water extract of Sargassum hemiphyllum as the sole treatment for allergic contact dermatitis – A case report

IF 1.7 Q2 Medicine Advances in integrative medicine Pub Date : 2024-09-01 DOI:10.1016/j.aimed.2024.06.003
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Abstract

Introduction

Corticosteroids remain the mainstay of treatment for contact dermatitis, but there is a practical need to provide alternatives to patients concerned about the safety of these drugs. Sargassum hemiphyllum, a very common brown macroalga found on coasts of the Greater China, has been shown to be an abundant source of anti-inflammatory substances.

Case description

Presented below is the use of a crude, S. hemiphyllum hot-water extract (SHHWE) as the sole treatment in a patient with widespread allergic contact dermatitis. A 47-year-old female beautician presented with widespread allergic contact dermatitis on upper abdomen. She refused corticosteroid therapy and preferred conservative, moisturizer-based treatments. The SHHWE was used as the sole moisturizer and the patient recovered uneventfully within 6 weeks without requiring any medications.

Conclusions

This case, for the first time, illustrates the feasibility of using a SHHWE as the main treatment for allergic contact dermatitis. Such extracts may be considered in these patients who opt for non-corticosteroid, symptomatic treatments under medical supervision.

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马尾藻热水提取物作为过敏性接触性皮炎的唯一治疗方法--病例报告
导言皮质类固醇仍然是治疗接触性皮炎的主要药物,但由于患者担心这些药物的安全性,因此有必要为他们提供替代药物。马尾藻(Sargassum hemiphyllum)是大中华地区沿海一种非常常见的褐色大型藻类,已被证明是抗炎物质的丰富来源。病例描述以下是使用粗制马尾藻热水提取物(SHHWE)作为广泛过敏性接触性皮炎患者的唯一治疗方法。一位 47 岁的女性美容师上腹部出现大面积过敏性接触性皮炎。她拒绝接受皮质类固醇治疗,更倾向于保守的保湿治疗。将 SHHWE 用作唯一的保湿剂,患者在 6 周内顺利康复,无需服用任何药物。对于在医生指导下选择非皮质类固醇对症治疗的患者,可以考虑使用这种提取物。
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来源期刊
Advances in integrative medicine
Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
3.20
自引率
11.80%
发文量
0
审稿时长
15 weeks
期刊介绍: Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.
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