Structured query language tool to identify untreated individuals with abdominal aortic aneurysms

Jenna Brambora MD , Sophia H. Roberts MD , Kanhua Yin MD, MPH , Ifeanyichukwu Okereke MD , Zachary Wanken MD, MS , Nathan Droz MD , Mohamed A. Zayed MD, PhD, MBA
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Abstract

Objective

Despite well-established guidelines for the diagnosis and surveillance of abdominal aortic aneurysms (AAAs), many patients are still not discovered until they have already sustained a rupture. It is estimated that as many as 50% of individuals with AAAs are undiagnosed until they present with a life-threatening rupture and hemorrhagic shock. Structured query language (SQL) is a tool that can scan existing electronic medical record (EMR) systems to identify patients with specific characteristics or morbidities. Here we evaluate the use of SQL to determine whether it can identify untreated patients with AAA disease and other vascular comorbidities.

Methods

An SQL disease discovery query code (Medtronic) was developed based on the clinical criteria recommendations of the United States Preventative Services Task Force for AAA screening (male sex; age, 65-75 years; and former/current smoking history). The code was then integrated with 18 International Classification of Diseases, 10th Revision (ICD-10) diagnostic codes for AAA and AAA-related diseases. Over 130 ICD-10 or Current Procedural Terminology (CPT) codes for previous aortic repair were overlaid as an exclusion criterion. The query was applied to 1 year of patient data (June 2021 to June 2022) at our single-center, university-affiliated, regional referral medical center. Manual chart review was performed on identified patients to confirm the incidence of AAA disease (aortic diameter ≥3.0 cm), as well as the incidence of other vascular conditions such as hypertension, coronary artery disease (CAD), peripheral arterial disease (PAD), and/or carotid artery stenosis (CAS).

Results

The SQL code identified a total of 457 patients (449 male, 8 female). Of these patients, 167 (36.5%) had confirmed AAAs with an average diameter of 4.2 cm (range, 3.0-9.7 cm), with a positive predictive value of 28.2%. Prior AAA repair, with either endovascular or open repair, was observed in 39 patients with AAAs (23.4%). Among the remaining untreated 128 patients, six (5 male, 1 female) met the traditional size criteria for repair, and time between last radiological assessment and last clinical follow-up was 4.8 ± 8.8 months. Interestingly, only 71 patients (55.5%) were evaluated by a vascular surgeon. Additionally, we observed that the SQL code identified concomitant PAD in 31 patients (18.5%), and CAS in 17 patients (10.1%). Among patients with treated and untreated AAAs, 26.8% had either PAD or CAS.

Conclusions

An SQL tool can be incorporated in modern healthcare systems to facilitate identification of patients with untreated AAA disease and other vascular comorbidities. Such tools can enhance prompt disease recognition, referral to vascular surgery specialists, and early implementation of appropriate surveillance and/or treatment algorithms.

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识别未经治疗的腹主动脉瘤患者的结构化查询语言工具
目标尽管腹主动脉瘤(AAA)的诊断和监测指南已经确立,但仍有许多患者直到动脉瘤破裂后才被发现。据估计,多达 50% 的腹主动脉瘤患者直到出现危及生命的破裂和失血性休克时才被诊断出来。结构化查询语言(SQL)是一种可以扫描现有电子病历(EMR)系统的工具,用于识别具有特定特征或病症的患者。方法根据美国预防服务工作组(United States Preventative Services Task Force)关于 AAA 筛查的临床标准建议(性别:男性;年龄:65-75 岁;既往/当前吸烟史)开发了一个 SQL 疾病发现查询代码(美敦力)。然后将该代码与 18 个 AAA 和 AAA 相关疾病的《国际疾病分类》第 10 次修订版(ICD-10)诊断代码整合在一起。作为排除标准,还叠加了 130 多个关于既往主动脉修复的 ICD-10 或现行程序术语 (CPT) 代码。该查询适用于我们大学附属地区转诊医疗中心的一年患者数据(2021 年 6 月至 2022 年 6 月)。对确定的患者进行了人工病历审查,以确认 AAA 疾病(主动脉直径≥3.0 厘米)的发病率,以及其他血管疾病(如高血压、冠状动脉疾病 (CAD)、外周动脉疾病 (PAD),和/或颈动脉狭窄 (CAS) 的发病率。)其中,167 名患者(36.5%)确诊为 AAA,平均直径为 4.2 厘米(范围为 3.0-9.7 厘米),阳性预测值为 28.2%。有 39 名 AAA 患者(23.4%)曾接受过 AAA 修复,包括血管内修复或开放式修复。在其余 128 名未经治疗的患者中,有 6 人(5 男 1 女)符合传统的修复尺寸标准,最后一次放射学评估与最后一次临床随访之间的时间间隔为 4.8 ± 8.8 个月。有趣的是,只有 71 名患者(55.5%)由血管外科医生进行了评估。此外,我们还观察到,SQL 代码识别出 31 例患者(18.5%)同时患有 PAD,17 例患者(10.1%)同时患有 CAS。结论SQL工具可用于现代医疗保健系统,以帮助识别患有未治疗的AAA疾病和其他血管合并症的患者。这种工具可以提高疾病识别的及时性,将患者转诊给血管外科专家,并及早实施适当的监测和/或治疗方案。
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