Role of bioinformatics databases and tools in radiation biology

Q1 Health Professions Radiation Medicine and Protection Pub Date : 2024-06-11 DOI:10.1016/j.radmp.2024.06.002
{"title":"Role of bioinformatics databases and tools in radiation biology","authors":"","doi":"10.1016/j.radmp.2024.06.002","DOIUrl":null,"url":null,"abstract":"<div><p>Bioinformatics has become increasingly integral to radiation biology, also known as radiobiology, providing substantial support through data storage, conversion, visualization, and sharing. This review aims to deepen understanding of bioinformatics application in radiobiology by introducing key databases and analytical tools in radiobiology, including general bioinformatics databases, radiobiology-specific databases, data processing tools, and statistical analysis tools for differentially expressed genes (DEGs) and LC/MS analysis. This review also discusses bioinformatics applications in radiobiological fields, such as radioresistance and immune cell enrichment. Despite these advances, challenges such as data interoperability remain. Methods and projects to address these issues, such as GeCo and GMQL, are also examined.</p></div>","PeriodicalId":34051,"journal":{"name":"Radiation Medicine and Protection","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666555724000522/pdfft?md5=2d9d5caefb88b1e417f08754cc8b301e&pid=1-s2.0-S2666555724000522-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation Medicine and Protection","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666555724000522","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Health Professions","Score":null,"Total":0}
引用次数: 0

Abstract

Bioinformatics has become increasingly integral to radiation biology, also known as radiobiology, providing substantial support through data storage, conversion, visualization, and sharing. This review aims to deepen understanding of bioinformatics application in radiobiology by introducing key databases and analytical tools in radiobiology, including general bioinformatics databases, radiobiology-specific databases, data processing tools, and statistical analysis tools for differentially expressed genes (DEGs) and LC/MS analysis. This review also discusses bioinformatics applications in radiobiological fields, such as radioresistance and immune cell enrichment. Despite these advances, challenges such as data interoperability remain. Methods and projects to address these issues, such as GeCo and GMQL, are also examined.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
生物信息学数据库和工具在辐射生物学中的作用
生物信息学已日益成为辐射生物学(又称放射生物学)不可或缺的一部分,通过数据存储、转换、可视化和共享提供了大量支持。本综述旨在通过介绍放射生物学中的关键数据库和分析工具,包括通用生物信息学数据库、放射生物学专用数据库、数据处理工具以及差异表达基因(DEGs)和 LC/MS 分析的统计分析工具,加深对放射生物学中生物信息学应用的理解。本综述还讨论了生物信息学在放射生物学领域的应用,如放射抗性和免疫细胞富集。尽管取得了这些进展,但数据互操作性等挑战依然存在。本文还探讨了解决这些问题的方法和项目,如 GeCo 和 GMQL。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Radiation Medicine and Protection
Radiation Medicine and Protection Health Professions-Emergency Medical Services
CiteScore
2.10
自引率
0.00%
发文量
0
审稿时长
103 days
期刊最新文献
Knockdown of the nucleoporin Nup50 protects cells against ionizing radiation through enhancing DNA-PKcs-mediated DNA damage repair DNA Damage Repair Meets Radiation: Better Radiotherapy Based on Study of the Underlying Mechanisms Tacrolimus may play a role in dermatitis and radiation-induced skin injury through cellular senescence Biophoton signaling in mediation of cell-to-cell communication and radiation-induced bystander effects Study on healthcare level and its relationship with medical radiation in China
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1