Bringing online adaptive radiotherapy to a standard C-arm linac

IF 3.4 Q2 ONCOLOGY Physics and Imaging in Radiation Oncology Pub Date : 2024-06-07 DOI:10.1016/j.phro.2024.100597

Maureen L. Groot Koerkamp, Gijsbert H. Bol, Petra S. Kroon, Lean L. Krikke, Tessa Harderwijk, Annelies J. Zoetelief, Annick Scheeren, Stefan van der Vegt, Annika Plat, Jochem Hes, Ineke B.A. van Gasteren, Esmee R.T. Renders, Reijer H.A. Rutgers, Saskia W. Kok, Joost van Kaam, Geja J. Schimmel-de Kogel, Gonda G. Sikkes, Dennis Winkel, Michael J. van Rijssel, André J.M. Wopereis, Bas W. Raaymakers

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Abstract

Current online adaptive radiotherapy (oART) workflows require dedicated equipment. Our aim was to develop and implement an oART workflow for a C-arm linac which can be performed using standard clinically available tools. A workflow was successfully developed and implemented. Three patients receiving palliative radiotherapy for bladder cancer were treated, with 33 of 35 total fractions being delivered with the cone-beam computed tomography (CBCT)-guided oART workflow. Average oART fraction duration was 24 min from start of CBCT acquisition to end of beam on. This work shows how oART could be performed without dedicated equipment, broadening oART availability for application at existing treatment machines.

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将在线自适应放射治疗引入标准 C 臂直列加速器

目前的在线自适应放射治疗（oART）工作流程需要专用设备。我们的目标是为 C 臂直列加速器开发并实施一种 oART 工作流程，该流程可使用标准的临床可用工具来执行。我们成功开发并实施了一套工作流程。我们对三名接受膀胱癌姑息放疗的患者进行了治疗，在锥形束计算机断层扫描（CBCT）引导的 oART 工作流程下，共进行了 35 次分割中的 33 次。从锥形束计算机断层扫描（CBCT）采集开始到光束照射结束，平均 oART 分段持续时间为 24 分钟。这项工作展示了如何在没有专用设备的情况下进行 oART，从而扩大了 oART 在现有治疗设备上的应用范围。

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