An Update on New and Existing Treatments for the Management of Melasma

IF 8.6 1区 医学 Q1 DERMATOLOGY American Journal of Clinical Dermatology Pub Date : 2024-06-19 DOI:10.1007/s40257-024-00863-2
Christian Gan, Michelle Rodrigues
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Abstract

Melasma is a chronic, acquired disorder of focal hypermelanosis that carries significant psychosocial impact and is challenging for both the patient and the treating practitioner to manage in the medium to long term. Multiple treatments have been explored, often in combination given the many aetiological factors involved in its pathogenesis. Therapeutic discoveries to treat melasma are a focal topic in the literature and include a range of modalities, with recent developments including updates on visible light photoprotection, non-hydroquinone depigmenting agents, oral tranexamic acid, chemical peels, and laser and energy-based device therapy for melasma. It is increasingly important yet challenging to remain up-to-date on the arsenal of treatments available for melasma to find an efficacious and well-tolerated option for our patients.

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关于治疗黄褐斑的新疗法和现有疗法的最新进展。
黄褐斑是一种慢性、后天性的局灶性黑素沉着症,对社会心理有重大影响,患者和治疗医生在中长期管理上都面临挑战。鉴于其发病机制涉及多种致病因素,人们探索了多种治疗方法,而且通常是综合治疗。治疗黄褐斑的新发现是文献中的一个焦点话题,包括一系列治疗方法,最近的发展包括更新可见光光保护、非氢醌脱色剂、口服氨甲环酸、化学换肤以及激光和能量设备治疗黄褐斑。了解黄褐斑治疗方法的最新进展,以便为患者找到疗效好、耐受性好的治疗方法,这一点越来越重要,但也越来越具有挑战性。
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来源期刊
CiteScore
15.20
自引率
2.70%
发文量
84
审稿时长
>12 weeks
期刊介绍: The American Journal of Clinical Dermatology is dedicated to evidence-based therapy and effective patient management in dermatology. It publishes critical review articles and clinically focused original research covering comprehensive aspects of dermatological conditions. The journal enhances visibility and educational value through features like Key Points summaries, plain language summaries, and various digital elements, ensuring accessibility and depth for a diverse readership.
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