Treatment of varicose great saphenous vein with endovenous laser alone or combined with eco-guided foam sclerotherapy: A randomized controlled trial.

IF 1.5 Phlebology Pub Date : 2024-12-01 Epub Date: 2024-06-18 DOI:10.1177/02683555241263224
Fabricio Duarte, Diego Mello de Souza, Ademar Regueira Filho, Laércio João Bazzanella, Flávia Del Castanhel, Getúlio Rodrigues de Oliveira Filho
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Abstract

Objectives: This study compares Endovenous Laser Ablation (EVLA) alone versus combined with ultrasound-guided foam sclerotherapy (UGFS) for Great Saphenous Vein (GSV) insufficiency. Methods: Sixty patients were randomly allocated to EVLA or EVLA-UGFS groups which focused on GSV occlusion rates, complications, additional treatments, and quality of life (QoL) changes. Results: Among 55 participants, the EVLA group had higher 12-month occlusion rates (92.3% vs. 75.8%, p = 0.11). Nervous injury (NI) was rarer in EVLA-UGFS (3.4% vs. 23.1%, p = 0.04). No significant difference in other complication rates (p > 0.05). QoL improved in both groups (p < 0.001). EVLA-UGFS required more subsequent procedures (24.1% vs. 7.7%, p = 0.03). Conclusions: EVLA and EVLA-UGFS effectively treat GSV insufficiency, enhancing QoL. The combined method reduces NI risk but may require more follow-up procedures.

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静脉腔内激光单独或与生态导引泡沫硬化疗法联合治疗大隐静脉曲张:随机对照试验。
研究目的:本研究比较了单纯静脉腔内激光消融术(EVLA)与超声引导下泡沫硬化疗法(UGFS)联合治疗大隐静脉(GSV)瓣膜功能不全的效果。方法:将 60 名患者随机分配到 EVLA 组或 EVLA-UGFS 组,重点关注 GSV 闭塞率、并发症、额外治疗和生活质量(QoL)变化。结果:在 55 名参与者中,EVLA 组的 12 个月闭塞率更高(92.3% 对 75.8%,P = 0.11)。EVLA-UGFS组较少发生神经损伤(NI)(3.4% 对 23.1%,P = 0.04)。其他并发症发生率无明显差异(P > 0.05)。两组患者的生活质量均有所改善(p < 0.001)。EVLA-UGFS 需要更多后续手术(24.1% 对 7.7%,p = 0.03)。结论:EVLA和EVLA-UGFS可有效治疗GSV功能不全,提高生活质量。联合方法降低了NI风险,但可能需要更多的后续手术。
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