A case report: A successfully treated erythrodermic mycosis fungoides with CHOP chemotherapy regiment and narrow band-UVB

IF 0.2 Q4 ONCOLOGY Current problems in cancer. Case reports Pub Date : 2024-06-06 DOI:10.1016/j.cpccr.2024.100300

Karina Survival Rofiq , Merlyna Savitri , Amira Rahmatika , Linda Astari , Ami Ashariati , Siprianus Ugroseno Yudho Bintoro

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Abstract

Mycosis fungoides (MF) is the most prevalent cutaneous T-cell lymphoma, with clinical symptoms comparable to erythroderma. An Indonesian female, 64-year-old, complained of itchy reddish skin and thick scales all over her body. She had a medical history of type 2 diabetes mellitus. Psoriasis vulgaris (erythroderma) was diagnosed and treated based on the signs and symptoms. The prognosis was not improved and a skin biopsy revealed mycosis fungoides (MF). Patient was treated with CHOP regiment, NB-UVB, and a combination of symptomatic therapies, which resulted in a favorable therapeutic response. Difficulties in diagnosis MF are caused by clinical signs and symptoms resembling dermatological disease. There is currently no cure for MF and the main purpose of treatment is illness management. Because the prognosis is poor at advance stage, an initial diagnosis and treatment are necessary to obtain a better prognosis.

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病例报告：用 CHOP 化疗方案和窄带紫外线照射成功治疗红皮病型真菌病的病例

真菌病（MF）是最常见的皮肤T细胞淋巴瘤，临床症状与红皮病相似。一名 64 岁的印度尼西亚女性主诉全身皮肤发红瘙痒，并有厚厚的鳞屑。她有 2 型糖尿病病史。根据症状和体征，诊断并治疗了寻常型银屑病（红皮病）。预后未见好转，皮肤活检发现了真菌病（MF）。患者接受了 CHOP 方案、NB-UVB 和综合对症疗法的治疗，取得了良好的治疗效果。由于临床症状和体征与皮肤病相似，因此对 MF 的诊断存在困难。中耳炎目前无法治愈，治疗的主要目的是控制病情。由于前期预后较差，因此有必要进行初步诊断和治疗，以获得更好的预后。

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