Rapid Assessment of the Need for Evidence: Applying the Principles of Value of Information to Research Prioritisation.

IF 4.4 3区 医学 Q1 ECONOMICS PharmacoEconomics Pub Date : 2024-09-01 Epub Date: 2024-06-20 DOI:10.1007/s40273-024-01403-w
David Glynn, Vijay S Gc, Karl Claxton, Chris Littlewood, Claire Rothery
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Abstract

We propose a short-cut heuristic approach to rapidly estimate value of information (VOI) using information commonly reported in a research funding application to make a case for the need for further evaluative research. We develop a "Rapid VOI" approach, which focuses on uncertainty in the primary outcome of clinical effectiveness and uses this to explore the health consequences of decision uncertainty. We develop a freely accessible online tool, Rapid Assessment of the Need for Evidence (RANE), to allow for the efficient computation of the value of research. As a case study, the method was applied to a proposal for research on shoulder pain rehabilitation. The analysis was included as part of a successful application for research funding to the UK National Institute for Health and Care Research. Our approach enables research funders and applicants to rapidly estimate the value of proposed research. Rapid VOI relies on information that is readily available and reported in research funding applications. Rapid VOI supports research prioritisation and commissioning decisions where there is insufficient time and resources available to develop and validate complex decision-analytic models. The method provides a practical means for implementing VOI in practice, thus providing a starting point for deliberation and contributing to the transparency and accountability of research prioritisation decisions.

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快速评估证据需求:将信息价值原则应用于确定研究重点。
我们提出了一种捷径启发式方法,利用研究资金申请中通常报告的信息快速估算信息价值(VOI),以证明进一步评估研究的必要性。我们开发了一种 "快速 VOI "方法,重点关注临床疗效这一主要结果的不确定性,并以此探讨决策不确定性对健康造成的影响。我们开发了一个可免费访问的在线工具--"证据需求快速评估"(RANE),以便有效计算研究价值。作为一项案例研究,我们将该方法应用于一项肩痛康复研究提案。分析结果作为成功申请研究基金的一部分,提交给了英国国家健康与护理研究所。我们的方法使研究资助者和申请者能够快速估算拟议研究的价值。快速 VOI 依赖于研究资金申请中随时可用和报告的信息。在没有足够的时间和资源来开发和验证复杂的决策分析模型的情况下,快速 VOI 可为研究优先级和委托决策提供支持。该方法为在实践中实施 VOI 提供了一种实用手段,从而为审议提供了一个起点,并有助于提高研究优 先次序决策的透明度和问责制。
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来源期刊
PharmacoEconomics
PharmacoEconomics 医学-药学
CiteScore
8.10
自引率
9.10%
发文量
85
审稿时长
6-12 weeks
期刊介绍: PharmacoEconomics is the benchmark journal for peer-reviewed, authoritative and practical articles on the application of pharmacoeconomics and quality-of-life assessment to optimum drug therapy and health outcomes. An invaluable source of applied pharmacoeconomic original research and educational material for the healthcare decision maker. PharmacoEconomics is dedicated to the clear communication of complex pharmacoeconomic issues related to patient care and drug utilization. PharmacoEconomics offers a range of additional features designed to increase the visibility, readership and educational value of the journal’s content. Each article is accompanied by a Key Points summary, giving a time-efficient overview of the content to a wide readership. Articles may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand the scientific content and overall implications of the article.
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