Benzoylation of Iota Carrageenan: Development of a Stable, Conductive, and Hydrophobic Drug Carrier with Reduced Toxicity and Improved Gel-Forming Ability

IF 2.5 4区 化学 Q3 POLYMER SCIENCE Macromolecular Chemistry and Physics Pub Date : 2024-06-21 DOI:10.1002/macp.202470024
Akanksha Bhatt, Shashank Kailkhura, Priyank Purohit
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Abstract

Front Cover: Hydrocolloids become hydrophobic hydrocolloids by the benzoylation process of iota carrageenan. This alters the gelling network's morphology and makes the gel's center more hydrophobic than the parent polymer. This allows the gel to ensure the high bioavailability of the medicine, which does not dissolve in water and causes low bioavailability of poorly soluble drugs. More details can be found in article 2400017 by Priyank Purohit and co-workers.

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Iota 卡拉胶的苯甲酰化:开发稳定、导电、疏水性药物载体,降低毒性并提高凝胶成型能力
封面:通过对异位卡拉胶进行苯甲酰化处理,水胶体变成了疏水性水胶体。这改变了胶凝网络的形态,使凝胶的中心比母体聚合物更疏水。这样,凝胶就能确保药物的高生物利用度,因为药物不溶于水,导致溶解性差的药物生物利用度较低。更多详情请见 Priyank Purohit 及其合作者撰写的文章 2400017。
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来源期刊
Macromolecular Chemistry and Physics
Macromolecular Chemistry and Physics 化学-高分子科学
CiteScore
4.30
自引率
4.00%
发文量
278
审稿时长
1.4 months
期刊介绍: Macromolecular Chemistry and Physics publishes in all areas of polymer science - from chemistry, physical chemistry, and physics of polymers to polymers in materials science. Beside an attractive mixture of high-quality Full Papers, Trends, and Highlights, the journal offers a unique article type dedicated to young scientists – Talent.
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