Review of Mixed Arterial Venous Leg Ulcers (MAVLU) Disease in Contemporary Practice.

Vascular and endovascular surgery Pub Date : 2024-10-01 Epub Date: 2024-06-24 DOI:10.1177/15385744241264336

Mohammed Alagha, Ahmmad Alfatih, Daniel Westby, Stewart R Walsh

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Abstract

Background: Mixed Arterial and Venous Leg Ulcers (MAVLU) are challenging. Clinical evidence specific to MAVLU management is scarce. We evaluated our recent experience with MAVLU patients and reviewed current data regarding MAVLU epidemiology, aetiology, diagnostic assessment and management options.

Methods: A prospective leg ulcer database was retrospectively interrogated to determine the prevalence and clinical outcome of MAVLU over 2-year period (2021-2022). The literature was reviewed to determine if optimal treatment strategies.

Results: 307 patients attended the ulcer clinic over a 2-year period. Most were venous leg ulcers (71%), 24% were arterial and 5% were MAVLU. The highest healing rate was in MAVLU (93%), followed by (74%) and (41%), in arterial and venous leg ulcer groups, respectively.

Conclusion: Evidence-based guidelines for MAVLU remain lacking. Well-developed randomised controlled trials are warranted to guide current clinical practice.

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当代实践中的混合动脉静脉性腿部溃疡 (MAVLU) 疾病回顾。

背景：动静脉混合型腿部溃疡（MAVLU）具有挑战性。有关混合性动静脉腿溃疡治疗的临床证据很少。我们评估了近期治疗混合型动静脉腿部溃疡患者的经验，并回顾了目前有关混合型动静脉腿部溃疡流行病学、病因学、诊断评估和治疗方案的数据：我们对一个前瞻性腿部溃疡数据库进行了回顾性调查，以确定两年内（2021-2022 年）MAVLU 的发病率和临床结果。此外，还查阅了相关文献，以确定最佳治疗策略：在两年时间里，有307名患者到溃疡诊所就诊。大部分为腿部静脉溃疡（71%），24%为动脉溃疡，5%为MAVLU。MAVLU的愈合率最高（93%），其次分别是动脉和静脉腿部溃疡组（74%）和（41%）：结论：MAVLU 仍然缺乏循证指南。结论：MAVLU 的循证指南仍然缺乏，有必要开展完善的随机对照试验来指导当前的临床实践。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Vascular and endovascular surgery

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