{"title":"Stimuli-responsive drug release of polyacrylic acid-coated silica–titania hollow nanoparticles","authors":"Semun Kim, Euiseok Jeong, Bomi Kim, Seungae Lee","doi":"10.1016/j.matlet.2024.136879","DOIUrl":null,"url":null,"abstract":"<div><p>Inorganic hollow nanoparticles have received a great deal of attention as nanocarriers for drug delivery system, but it is still challenging to control the drug release time and achieve high drug delivery efficiency. In this study, we intend to build a controllable smart drug delivery system that delivers drugs to a desired location for a desired time using a stimulus-responsive material. Polyacrylic acid (PAA), a pH-responsive material, is coated on the silica–titania hollow nanoparticles (HNPs) to acquire stimulus-responsive material for controlled drug release.</p></div>","PeriodicalId":384,"journal":{"name":"Materials Letters","volume":null,"pages":null},"PeriodicalIF":2.7000,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Letters","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167577X24010188","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Inorganic hollow nanoparticles have received a great deal of attention as nanocarriers for drug delivery system, but it is still challenging to control the drug release time and achieve high drug delivery efficiency. In this study, we intend to build a controllable smart drug delivery system that delivers drugs to a desired location for a desired time using a stimulus-responsive material. Polyacrylic acid (PAA), a pH-responsive material, is coated on the silica–titania hollow nanoparticles (HNPs) to acquire stimulus-responsive material for controlled drug release.
期刊介绍：
Materials Letters has an open access mirror journal Materials Letters: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
Materials Letters is dedicated to publishing novel, cutting edge reports of broad interest to the materials community. The journal provides a forum for materials scientists and engineers, physicists, and chemists to rapidly communicate on the most important topics in the field of materials.
Contributions include, but are not limited to, a variety of topics such as:
• Materials - Metals and alloys, amorphous solids, ceramics, composites, polymers, semiconductors
• Applications - Structural, opto-electronic, magnetic, medical, MEMS, sensors, smart
• Characterization - Analytical, microscopy, scanning probes, nanoscopic, optical, electrical, magnetic, acoustic, spectroscopic, diffraction
• Novel Materials - Micro and nanostructures (nanowires, nanotubes, nanoparticles), nanocomposites, thin films, superlattices, quantum dots.
• Processing - Crystal growth, thin film processing, sol-gel processing, mechanical processing, assembly, nanocrystalline processing.
• Properties - Mechanical, magnetic, optical, electrical, ferroelectric, thermal, interfacial, transport, thermodynamic
• Synthesis - Quenching, solid state, solidification, solution synthesis, vapor deposition, high pressure, explosive
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