Vanessa Gomes Brandão Rodrigues MD , Whesley Tanor Silva MSc , Ana Caiane Rocha da Silva MSc , Patrícia Cardoso Campos MSc , Luciana Martins de Mello Santos MSc , Ana Cristina Rodrigues Lacerda PhD , Frederico Lopes Alves MD , Emílio Henrique Barroso Maciel MD , Maria Cecília Sales Mendes Prates MD , Henrique Silveira Costa PhD , Vanessa Pereira de Lima PhD , Vanessa Amaral Mendonça PhD , Pedro Henrique Scheidt Figueiredo PhD
{"title":"Relationship Between Residual Diuresis and Sarcopenia in Patients on Hemodialysis","authors":"Vanessa Gomes Brandão Rodrigues MD , Whesley Tanor Silva MSc , Ana Caiane Rocha da Silva MSc , Patrícia Cardoso Campos MSc , Luciana Martins de Mello Santos MSc , Ana Cristina Rodrigues Lacerda PhD , Frederico Lopes Alves MD , Emílio Henrique Barroso Maciel MD , Maria Cecília Sales Mendes Prates MD , Henrique Silveira Costa PhD , Vanessa Pereira de Lima PhD , Vanessa Amaral Mendonça PhD , Pedro Henrique Scheidt Figueiredo PhD","doi":"10.1053/j.jrn.2024.06.006","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To assess the association of residual diuresis with sarcopenia in patients with chronic kidney disease on hemodialysis.</div></div><div><h3>Methods</h3><div>Through a cross-sectional study, patients on hemodialysis were subjected to a Dual-Energy Radiologic Absorption examination to record muscle mass. Based on the volume of urine collected in 24 hours, patients were classified as anuric (diuresis ≤100 mL/day) or nonanuric (diuresis > 100 mL/day). Functional performance was evaluated by Short Physical Performance Battery (SPPB) and muscle strength by handgrip strength and 5-repetition sit-to-stand test. The association between the absence of residual urine and the presence of sarcopenia, low SPPB, and low muscle strength was analyzed using a binary logistic regression model.</div></div><div><h3>Results</h3><div>Ninety-two patients, with a mean age of 54.4 years (95% confidence interval [CI] 51.3-57.4) and with a mean diuresis volume of 476.3 mL/day (95% CI 320.4-632.2) were evaluated (48 anuric and 44 nonanuric). Anuric patients had a 2.77 (95% CI 1.14-6.73) times greater probability of sarcopenia and had a 3.55 (1.14-11.0) times greater probability of low SPPB regardless of gender, age, and time on dialysis. Gender was the other associated variable for the presence of sarcopenia, with males having a 3.30 (95% CI 1.34-8.13) times higher risk. There were no associations with muscle strength.</div></div><div><h3>Conclusion</h3><div>The absence of residual diuresis in patients on hemodialysis is associated with a higher risk of sarcopenia and low functional performance.</div></div>","PeriodicalId":50066,"journal":{"name":"Journal of Renal Nutrition","volume":"36 1","pages":"Pages 112-120"},"PeriodicalIF":3.2000,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Renal Nutrition","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1051227624001389","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
To assess the association of residual diuresis with sarcopenia in patients with chronic kidney disease on hemodialysis.
Methods
Through a cross-sectional study, patients on hemodialysis were subjected to a Dual-Energy Radiologic Absorption examination to record muscle mass. Based on the volume of urine collected in 24 hours, patients were classified as anuric (diuresis ≤100 mL/day) or nonanuric (diuresis > 100 mL/day). Functional performance was evaluated by Short Physical Performance Battery (SPPB) and muscle strength by handgrip strength and 5-repetition sit-to-stand test. The association between the absence of residual urine and the presence of sarcopenia, low SPPB, and low muscle strength was analyzed using a binary logistic regression model.
Results
Ninety-two patients, with a mean age of 54.4 years (95% confidence interval [CI] 51.3-57.4) and with a mean diuresis volume of 476.3 mL/day (95% CI 320.4-632.2) were evaluated (48 anuric and 44 nonanuric). Anuric patients had a 2.77 (95% CI 1.14-6.73) times greater probability of sarcopenia and had a 3.55 (1.14-11.0) times greater probability of low SPPB regardless of gender, age, and time on dialysis. Gender was the other associated variable for the presence of sarcopenia, with males having a 3.30 (95% CI 1.34-8.13) times higher risk. There were no associations with muscle strength.
Conclusion
The absence of residual diuresis in patients on hemodialysis is associated with a higher risk of sarcopenia and low functional performance.
期刊介绍:
The Journal of Renal Nutrition is devoted exclusively to renal nutrition science and renal dietetics. Its content is appropriate for nutritionists, physicians and researchers working in nephrology. Each issue contains a state-of-the-art review, original research, articles on the clinical management and education of patients, a current literature review, and nutritional analysis of food products that have clinical relevance.