The first report and biological characterization of Avian Orthoavulavirus 16 in wild migratory waterfowl and domestic poultry in China reveal a potential threat to birds.

IF 2.5 2区 农林科学 Q1 VETERINARY SCIENCES Avian Pathology Pub Date : 2025-02-01 Epub Date: 2024-07-17 DOI:10.1080/03079457.2024.2373366
Yuxin Sha, Weiwen Yan, Xinxin Liu, Haoran Chai, Jianjun Chen, Hongjin Li, Mengjun Wang, Shanshan Jiang, Sijie Wang, Yongning Ren, Hongli Li, Yifei Liu, Tobias Stoeger, Abdul Wajid, Aleksandar Dodovski, Chao Gao, Claro N Mingala, Dmitry B Andreychuk, Renfu Yin
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Abstract

Research highlights: First confirmation of AOAV-16 in domestic and wild birds in China.AOAV-16 are low virulent viruses for chickens.Co-circulation/co-infection of AOAV-16 and H9N2 subtype AIV enhanced pathogenicity.Different intergenic sequences and recombination events exist within AOAV-16.

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中国首次报告了野生候鸟水禽和家禽中的禽正沟病毒 16,其生物学特征揭示了该病毒对鸟类的潜在威胁。
摘要副黏液病毒科(Paramyxoviridae)中的阿乌拉病毒(Avulavirus)至少包括 22 个不同的种类,已知可在多种禽类中引起不同类型的感染,甚至致命。尽管近十年来从世界各地的野生鸟类和家禽中发现了多达 10 个不同的新种,但人们对家禽和野生鸟类中 Avulavirus -2 至 22 种病毒的遗传和生物学信息了解有限,这些病毒在鸟类中的疾病意义也尚未完全确定。本研究旨在利用 PCR、病毒分离和测序技术对 2014 年至 2022 年期间从中国不同地点采集的野鸟和家禽中的禽正沟病毒 16(AOAV-16)进行遗传学和生物学鉴定。在分离到的5株AOAV-16(Y1至Y5)中,只有Y4株的血凝(HA)结果为阴性。除 Y3 株与 H9N2 亚型禽流感病毒(AIV)同时被检测到外,其他分离株对鸡均为低毒性病毒。此外,AOAV-16 病毒的 HN 和 L 基因之间至少存在四种不同类型的基因间序列(IGS),并且存在重组事件以及野生候鸟的种间传播。这些发现和其他已报道的 AOAV-16 株系的结果建议采取严格的控制措施,限制野生候鸟与家禽的接触,这意味着对商品家禽的潜在威胁,甚至是对全球公共卫生的挑战。
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来源期刊
Avian Pathology
Avian Pathology 农林科学-兽医学
CiteScore
4.50
自引率
10.70%
发文量
68
审稿时长
1 months
期刊介绍: Avian Pathology is the official journal of the World Veterinary Poultry Association and, since its first publication in 1972, has been a leading international journal for poultry disease scientists. It publishes material relevant to the entire field of infectious and non-infectious diseases of poultry and other birds. Accepted manuscripts will contribute novel data of interest to an international readership and will add significantly to knowledge and understanding of diseases, old or new. Subject areas include pathology, diagnosis, detection and characterisation of pathogens, infections of possible zoonotic importance, epidemiology, innate and immune responses, vaccines, gene sequences, genetics in relation to disease and physiological and biochemical changes in response to disease. First and subsequent reports of well-recognized diseases within a country are not acceptable unless they also include substantial new information about the disease or pathogen. Manuscripts on wild or pet birds should describe disease or pathogens in a significant number of birds, recognizing/suggesting serious potential impact on that species or that the disease or pathogen is of demonstrable relevance to poultry. Manuscripts on food-borne microorganisms acquired during or after processing, and those that catalogue the occurrence or properties of microorganisms, are unlikely to be considered for publication in the absence of data linking them to avian disease.
期刊最新文献
The first report and biological characterization of Avian Orthoavulavirus 16 in wild migratory waterfowl and domestic poultry in China reveal a potential threat to birds. Very virulent infectious bursal disease virus infection triggered microscopic changes, apoptosis, and inflammatory cytokines imbalance in chicken spleen and thymus. Pathogenicity of duck circovirus and novel goose parvovirus co-infection in SPF ducks. A vaccine programme comprising GA08 (GI-27) and Mass (GI-1) strains prevents DMV1639 (GI-17) infectious bronchitis virus transmission among broiler chickens. In vitro antiviral activity of NanB bacterial sialidase against avian influenza H9N2 virus in MDCK cells.
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