Herbal and Non-Herbal Dietary Supplements for Psychiatric Indications: Considerations in Liver Transplantation.

IF 5.5 2区 医学 Q1 PSYCHIATRY Current Psychiatry Reports Pub Date : 2024-08-01 Epub Date: 2024-06-28 DOI:10.1007/s11920-024-01517-0
Shivali Patel, Kinza Tareen, Chandni Patel, Amy Rosinski
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Abstract

Purpose of review: Traditional, complementary, and integrative medicine (TCIM) modalities are widely employed. However, TCIM, specifically herbal and non-herbal dietary supplements, can pose challenges in the context of organ transplantation. In this review, we discuss common supplements used for psychiatric purposes and highlight important considerations for candidates and recipients of liver transplants.

Recent findings: Ashwagandha, kava kava, green tea extract, skullcap, turmeric, and valerian have known idiosyncratic hepatotoxic potential and may complicate the liver transplantation course. Multiple supplements reportedly carry a lower risk of hepatotoxicity, though evidence for widespread use in those at risk for or with hepatic impairment is limited. Psychiatrists caring for candidates and recipients of liver transplants must recognize that patients may find supplements helpful in alleviating psychiatric symptoms, despite an overall limited evidence base. Evaluating benefit versus risk ratios and reviewing drug-drug interactions is essential to promote transplant candidacy and mitigate the possibility of native or graft liver dysfunction.

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用于精神疾病的草药和非草药膳食补充剂:肝移植中的注意事项。
审查目的:传统、补充和综合医学(TCIM)模式被广泛采用。然而,传统、补充和综合医学,特别是草药和非草药膳食补充剂,可能会给器官移植带来挑战。在这篇综述中,我们讨论了用于精神治疗的常见补充剂,并强调了肝移植候选者和受者的重要注意事项:芦根、卡瓦卡瓦、绿茶提取物、头盖骨、姜黄和缬草具有已知的特异性肝毒性潜能,可能会使肝移植过程复杂化。据报道,多种补充剂的肝毒性风险较低,但在有肝损伤风险或肝损伤患者中广泛使用的证据有限。为肝移植候选者和受者提供护理的精神科医生必须认识到,尽管总体证据基础有限,但患者可能会发现补充剂有助于缓解精神症状。评估获益与风险的比率以及审查药物之间的相互作用,对于促进移植候选资格和减少原肝或移植肝功能障碍的可能性至关重要。
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来源期刊
CiteScore
11.30
自引率
3.00%
发文量
68
审稿时长
6-12 weeks
期刊介绍: This journal aims to review the most important, recently published research in psychiatry. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by psychiatric disorders. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anxiety, medicopsychiatric disorders, and schizophrenia and other related psychotic disorders. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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