Impact of hospital-community diabetes management intervention in Central Region, Ghana: A retrospective study

IF 6.1 3区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetes research and clinical practice Pub Date : 2024-07-01 DOI:10.1016/j.diabres.2024.111762
Julius Waamsasiko Adong , David Nana Adjei , Martin Nyaaba Adokiya , Charles Agyemang
{"title":"Impact of hospital-community diabetes management intervention in Central Region, Ghana: A retrospective study","authors":"Julius Waamsasiko Adong ,&nbsp;David Nana Adjei ,&nbsp;Martin Nyaaba Adokiya ,&nbsp;Charles Agyemang","doi":"10.1016/j.diabres.2024.111762","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Effective diabetes management remains suboptimal in low-resourced countries including Ghana. We determined the effectiveness of hospital-community link diabetes management intervention on glycaemic control and other outcomes.</p></div><div><h3>Methods</h3><p>A retrospective study design, using secondary data from the Ghana-Netherlands for Health Foundation diabetes programme. The z-test was used for proportions, to compare parameters between baseline (2017) and endpoint (2022). The Friedman test was used to assess changes in blood glucose levels, and the multivariable Logistic regression to identify factors associated with blood glucose control.</p></div><div><h3>Results</h3><p>Analyses of 251 clinical records showed decline in median blood glucose levels across six years from 8.8 mmol/L (7.2–12.9) in 2017 to 6.5 mmol/L (5.7–7.2) (p = 0.001) in 2022, recording 43 % increase in patients attaining glycaemic control in 2022 (p = 0.001). The Friedman test showed significant reduction in glucose levels (χ<sup>2</sup> = 319.2, p = 0.001), with an effect size of 0.25 using the Kendall test. The logistic regression analyses revealed that patients on metformin and Glibenclamide combination were more likely to achieve glycaemic control than those on metformin monotherapy (adjusted OR = 7.30, 95 % CI 2.31–23.01, p = 0.001).</p></div><div><h3>Conclusion</h3><p>The intervention achieved significant reduction in blood glucose levels. Patients with diabetes benefit from the hospital-community link diabetes management intervention regarding glycaemic control.</p></div>","PeriodicalId":11249,"journal":{"name":"Diabetes research and clinical practice","volume":null,"pages":null},"PeriodicalIF":6.1000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diabetes research and clinical practice","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0168822724006727","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0

Abstract

Objective

Effective diabetes management remains suboptimal in low-resourced countries including Ghana. We determined the effectiveness of hospital-community link diabetes management intervention on glycaemic control and other outcomes.

Methods

A retrospective study design, using secondary data from the Ghana-Netherlands for Health Foundation diabetes programme. The z-test was used for proportions, to compare parameters between baseline (2017) and endpoint (2022). The Friedman test was used to assess changes in blood glucose levels, and the multivariable Logistic regression to identify factors associated with blood glucose control.

Results

Analyses of 251 clinical records showed decline in median blood glucose levels across six years from 8.8 mmol/L (7.2–12.9) in 2017 to 6.5 mmol/L (5.7–7.2) (p = 0.001) in 2022, recording 43 % increase in patients attaining glycaemic control in 2022 (p = 0.001). The Friedman test showed significant reduction in glucose levels (χ2 = 319.2, p = 0.001), with an effect size of 0.25 using the Kendall test. The logistic regression analyses revealed that patients on metformin and Glibenclamide combination were more likely to achieve glycaemic control than those on metformin monotherapy (adjusted OR = 7.30, 95 % CI 2.31–23.01, p = 0.001).

Conclusion

The intervention achieved significant reduction in blood glucose levels. Patients with diabetes benefit from the hospital-community link diabetes management intervention regarding glycaemic control.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
加纳中部地区医院-社区糖尿病管理干预措施的影响:回顾性研究。
目的:在包括加纳在内的资源匮乏国家,有效的糖尿病管理仍然不尽如人意。我们确定了医院-社区联系糖尿病管理干预对血糖控制和其他结果的有效性:方法:采用回顾性研究设计,使用加纳-荷兰健康基金会糖尿病项目的二手数据。比例采用z检验,以比较基线(2017年)和终点(2022年)之间的参数。弗里德曼检验用于评估血糖水平的变化,多变量逻辑回归用于确定与血糖控制相关的因素:对251份临床记录的分析表明,六年间血糖水平中位数从2017年的8.8 mmol/L (7.2-12.9)降至2022年的6.5 mmol/L (5.7-7.2)(p = 0.001),2022年达到血糖控制的患者增加了43%(p = 0.001)。弗里德曼检验显示血糖水平明显降低(χ2 = 319.2,p = 0.001),肯德尔检验的效应大小为 0.25。逻辑回归分析显示,二甲双胍和格列本脲联合治疗的患者比二甲双胍单药治疗的患者更有可能实现血糖控制(调整 OR = 7.30,95 % CI 2.31-23.01,p = 0.001):干预措施明显降低了血糖水平。糖尿病患者在血糖控制方面可从医院-社区糖尿病管理干预中获益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Diabetes research and clinical practice
Diabetes research and clinical practice 医学-内分泌学与代谢
CiteScore
10.30
自引率
3.90%
发文量
862
审稿时长
32 days
期刊介绍: Diabetes Research and Clinical Practice is an international journal for health-care providers and clinically oriented researchers that publishes high-quality original research articles and expert reviews in diabetes and related areas. The role of the journal is to provide a venue for dissemination of knowledge and discussion of topics related to diabetes clinical research and patient care. Topics of focus include translational science, genetics, immunology, nutrition, psychosocial research, epidemiology, prevention, socio-economic research, complications, new treatments, technologies and therapy.
期刊最新文献
Computed tomography-based body composition indicative of diabetes after hypertriglyceridemic acute pancreatitis Physical activity and sedentary behaviour in relation to body composition, estimated insulin sensitivity and arterial stiffness in adults with type 1 diabetes Role of microRNAs in diabetic foot ulcers: Mechanisms and possible interventions Early life socioeconomic inequalities and type 2 diabetes incidence: Longitudinal analyses in the Maastricht study Editorial Board
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1