Biliary Leaks: Multidisciplinary Approach to Diagnosis and Treatment.

IF 5.2 1区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Radiographics Pub Date : 2024-07-01 DOI:10.1148/rg.230155
Philip J Schertz, Christopher A Mao, Kade D Derrick, Federico Galar, Carlos B Ortiz, John A Walker, Jorge E Lopera
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Abstract

Bile leaks arise from various causes such as trauma, complications after hepatobiliary surgery, and intrahepatic malignancies or their associated liver-directed treatments. Bile leaks can result in significant morbidity and mortality. Delayed diagnosis is not uncommon due to nonspecific manifestations; therefore, a high clinical suspicion is needed. A multidisciplinary approach for treatment of biliary leaks with prompt referral to tertiary care centers with experienced hepatobiliary surgeons, advanced endoscopists, and interventional radiologists is needed to address these challenging complications. Management of biliary leaks can range from conservative management to open surgical repair. Minimally invasive procedures play a crucial role in biliary leak treatment, and the interventional radiologist can help guide appropriate management on the basis of a clear understanding of the pathophysiology of biliary leaks and a current knowledge of the armamentarium of treatment options. In most cases, a simple diversion of bile to decompress the biliary system may prove effective. However, persistent and high-output biliary leaks require delineation of the source with tailored treatment options to control the leak. This may be done by additional diversions, occluding the source, reestablishing connections, or using a combination of therapies to bridge to more definitive surgical interventions. The authors describe the different treatment options and emphasize the role of interventional radiology. ©RSNA, 2024.

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胆漏:诊断和治疗的多学科方法。
胆漏有多种原因,如外伤、肝胆手术后并发症、肝内恶性肿瘤或与之相关的肝脏导向治疗。胆漏可导致严重的发病率和死亡率。由于非特异性表现,延误诊断的情况并不少见;因此,临床上需要高度怀疑。需要采用多学科方法治疗胆漏,并及时转诊至拥有经验丰富的肝胆外科医生、高级内镜医师和介入放射医师的三级医疗中心,以应对这些具有挑战性的并发症。胆漏的治疗包括保守治疗和开放性手术修复。微创手术在胆漏治疗中起着至关重要的作用,介入放射科医生可以在清楚了解胆漏病理生理学和当前治疗方案知识的基础上,帮助指导适当的治疗。在大多数情况下,简单的胆汁转流给胆道系统减压可能会被证明是有效的。但是,对于持续性和高输出胆漏,则需要确定胆漏源头,并采取有针对性的治疗方案来控制胆漏。这可以通过额外的分流、闭塞源头、重建连接或使用综合疗法来实现,从而为更彻底的外科干预架起桥梁。作者介绍了不同的治疗方案,并强调了介入放射学的作用。©RSNA,2024。
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来源期刊
Radiographics
Radiographics 医学-核医学
CiteScore
8.20
自引率
5.50%
发文量
224
审稿时长
4-8 weeks
期刊介绍: Launched by the Radiological Society of North America (RSNA) in 1981, RadioGraphics is one of the premier education journals in diagnostic radiology. Each bimonthly issue features 15–20 practice-focused articles spanning the full spectrum of radiologic subspecialties and addressing topics such as diagnostic imaging techniques, imaging features of a disease or group of diseases, radiologic-pathologic correlation, practice policy and quality initiatives, imaging physics, informatics, and lifelong learning. A special issue, a monograph focused on a single subspecialty or on a crossover topic of interest to multiple subspecialties, is published each October. Each issue offers more than a dozen opportunities to earn continuing medical education credits that qualify for AMA PRA Category 1 CreditTM and all online activities can be applied toward the ABR MOC Self-Assessment Requirement.
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