Regional variation in bone mineral density of the distal radius

IF 2.5 Q3 ENDOCRINOLOGY & METABOLISM Osteoporosis and Sarcopenia Pub Date : 2024-06-01 DOI:10.1016/j.afos.2024.03.001
Helen Morgan, Katy Knight, Robert Meertens
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Abstract

Objectives

This study investigates the regional variation in areal bone mineral density (aBMD) at the distal radius, a critical site for osteoporosis-related fractures. Understanding aBMD distribution is essential for accurate diagnosis and management of osteoporosis.

Methods

The study involved 261 participants aged over 50. Using dual-energy X-ray absorptiometry (DXA) scans, aBMD was recorded across contiguous regions of the distal radius. Factors considered include age, sex, and hand dominance, providing a comprehensive view of aBMD distribution.

Results

The findings indicated a consistent pattern in aBMD distribution along the radius, with a plateau around the one-third distance from the wrist. Notably, significant differences in aBMD were observed between age groups, especially among post-menopausal women. The study also recorded minor variations in aBMD between dominant and non-dominant forearms.

Conclusions

The study's insights into aBMD variation at the distal radius have implications for osteoporosis research and clinical diagnosis. It highlights the importance of standardized region of interest placement in DXA scans for accurate assessment.

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桡骨远端骨矿密度的区域差异
目的:本研究调查了桡骨远端骨矿密度(aBMD)的区域性变化,桡骨远端是骨质疏松症相关骨折的关键部位。了解 aBMD 的分布对于准确诊断和管理骨质疏松症至关重要。使用双能 X 射线吸收测定法(DXA)扫描,记录桡骨远端连续区域的 aBMD。结果研究结果表明,桡骨的 aBMD 分布具有一致的模式,在距腕部三分之一处出现高原。值得注意的是,不同年龄组之间的 aBMD 存在明显差异,尤其是绝经后妇女。该研究还记录了优势前臂和非优势前臂之间在 aBMD 上的微小差异。它强调了在 DXA 扫描中标准化感兴趣区位置对准确评估的重要性。
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来源期刊
Osteoporosis and Sarcopenia
Osteoporosis and Sarcopenia Orthopedics, Sports Medicine and Rehabilitation, Endocrinology, Diabetes and Metabolism, Obstetrics, Gynecology and Women's Health, Geriatrics and Gerontology
自引率
5.00%
发文量
23
审稿时长
66 days
期刊最新文献
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