Optimizing the feasibility of polyvinyl alcohol-potassium iodine gel for medical dosimeter.

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Biomedical Physics & Engineering Express Pub Date : 2024-07-10 DOI:10.1088/2057-1976/ad5db0
Khalid A Rabaeh, Ruba K A Qawouq, Molham M Eyadeh, Moneeb T M Shatnawi
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Abstract

This work aims to improve the post stabilty of reusable potassium iodide hydrogel dosimter. A reusable and low-cost radiochromic dosimeter containing a gel matrix of polyvinyl alcohol, potassium iodide dye, froctose as reducing agent and glutaraldehyde as cross-linking agent was developed for dose calibration in radiotherapy. The gel samples were exposed to different absorbed doses using a medical linear acceleration. UV-vis Spectrophotometry was utilized to investigate the changes in optical-properties of irradiated gels with regard to peak wavelength of 353 nm. The stability of the gel (one of the most limitation of using this dosimeter) was improved significantly by the addition of certain concentrations of dimethyl sulfoxide. The two-dimensional optical imaging system of charge-coupled-device (CCD) camera with a uniform RGB light-emitting-diode (LED) array source was used for diffusion coefficient purpose using two dimensional gel template. The value of diffusion coefficient reported is significant and highly reduced compared with other dosimeters reported in the literatures. Moreover, heating the improved gels to certain temperatures results in resetting their optical properties, which makes it possible to reuse for multiple times.

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优化用于医用剂量计的聚乙烯醇-碘化钾凝胶的可行性。
这项研究旨在提高可重复使用碘化钾水凝胶剂量计的后期稳定性。该研究开发了一种可重复使用的低成本放射性变色剂量计,其中含有聚乙烯醇凝胶基质、碘化钾染料、作为还原剂的泡腾糖和作为交联剂的戊二醛,用于放射治疗中的剂量校准。使用医用线性加速器对凝胶样品进行不同吸收剂量的照射。利用紫外可见分光光度法研究了辐照凝胶在峰值波长 353 纳米处的光学特性变化。通过添加一定浓度的二甲基亚砜,凝胶的稳定性(使用这种剂量计的最大限制之一)得到了显著改善。利用电荷耦合器件(CCD)照相机和均匀的 RGB 发光二极管(LED)阵列光源的二维光学成像系统,使用二维凝胶模板计算扩散系数。与文献中报道的其他剂量计相比,报告的扩散系数值显著降低。此外,将改进后的凝胶加热到一定温度可重置其光学特性,从而使其可以多次重复使用。
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来源期刊
Biomedical Physics & Engineering Express
Biomedical Physics & Engineering Express RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.80
自引率
0.00%
发文量
153
期刊介绍: BPEX is an inclusive, international, multidisciplinary journal devoted to publishing new research on any application of physics and/or engineering in medicine and/or biology. Characterized by a broad geographical coverage and a fast-track peer-review process, relevant topics include all aspects of biophysics, medical physics and biomedical engineering. Papers that are almost entirely clinical or biological in their focus are not suitable. The journal has an emphasis on publishing interdisciplinary work and bringing research fields together, encompassing experimental, theoretical and computational work.
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