{"title":"Visual Inspection with Acetic Acid Positivity in Screening and Early Detection of Cervical Dysplasia in Africa, 2023: A Meta-Analysis.","authors":"Yohannes Fikadu Geda, Yirgalem Yosef Lamiso, Tamirat Melis Berhe, Seid Jemal Mohammed, Samuel Ejeta Chibsa, Daniel Adane Endalew, Kenzudin Assfa Mossa, Seblework Abeje, Mustefa Adem Hussen, Molalign Mesele Gesesse","doi":"10.4314/ejhs.v34i1.2","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Visual Inspection with Acetic acid (VIA) is the best feasible method of screening and early detecting for cervical dysplasia for resource limited settings like Africa. There is no study that can represent Africa on VIA positivity. Therefore, this metaanalysis was planned to verify the best available articles to pool the visual inspection with acetic acid positivity in screening and early detection of cervical dysplasia in Africa.</p><p><strong>Methods: </strong>The Cochrane Library, Web of Science, PubMed, Scopus, free Google database search engines, Google Scholar, and Science Direct databases were used to conduct a true search of this research article. STATA version 14.0 was used to do the metaanalysis. This meta-analysis was registered in PROSPERO database under the identity pf CRD42023392197.</p><p><strong>Result: </strong>This meta-analysis analyzed data from 21,066 women who had VIA examination to estimate the pooled VIA positivity in Africa. The overall pooled effect estimate of VIA positivity in Africa was 11.93 (95%CI: 11.48-12.37). Age <16 year during first intercourse 2.58(95%CI: 1.53-3.62), lifetime sexual partner ≥2 3.92(95%CI: 2.05-5.78) and HIV positivity 2.92(95%CI: 1.72-4.12) were the significant variables which influence VIA positivity.</p><p><strong>Conclusion: </strong>Overall pooled effect estimate of VIA positivity in Africa was high compared to other continents. The main factors that affect VIA positivity are age at first sexual contact being under 16 years old, the number of lifetime sexual partners being at least two, and HIV positivity. Therefore, the WHO's goal of creating Africa free of cervical cancer is still one that requires significant effort.</p>","PeriodicalId":12003,"journal":{"name":"Ethiopian Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217789/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ethiopian Journal of Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/ejhs.v34i1.2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Visual Inspection with Acetic acid (VIA) is the best feasible method of screening and early detecting for cervical dysplasia for resource limited settings like Africa. There is no study that can represent Africa on VIA positivity. Therefore, this metaanalysis was planned to verify the best available articles to pool the visual inspection with acetic acid positivity in screening and early detection of cervical dysplasia in Africa.
Methods: The Cochrane Library, Web of Science, PubMed, Scopus, free Google database search engines, Google Scholar, and Science Direct databases were used to conduct a true search of this research article. STATA version 14.0 was used to do the metaanalysis. This meta-analysis was registered in PROSPERO database under the identity pf CRD42023392197.
Result: This meta-analysis analyzed data from 21,066 women who had VIA examination to estimate the pooled VIA positivity in Africa. The overall pooled effect estimate of VIA positivity in Africa was 11.93 (95%CI: 11.48-12.37). Age <16 year during first intercourse 2.58(95%CI: 1.53-3.62), lifetime sexual partner ≥2 3.92(95%CI: 2.05-5.78) and HIV positivity 2.92(95%CI: 1.72-4.12) were the significant variables which influence VIA positivity.
Conclusion: Overall pooled effect estimate of VIA positivity in Africa was high compared to other continents. The main factors that affect VIA positivity are age at first sexual contact being under 16 years old, the number of lifetime sexual partners being at least two, and HIV positivity. Therefore, the WHO's goal of creating Africa free of cervical cancer is still one that requires significant effort.
背景:在非洲等资源有限的地区,醋酸目视检查(VIA)是筛查和早期发现宫颈发育不良的最佳可行方法。目前还没有一项研究能代表非洲的 VIA 阳性率。因此,本荟萃分析计划验证现有的最佳文章,以汇集醋酸目检阳性在非洲宫颈发育不良筛查和早期检测中的应用:使用 Cochrane Library、Web of Science、PubMed、Scopus、Google 免费数据库搜索引擎、Google Scholar 和 Science Direct 数据库对本研究文章进行了真实检索。使用 STATA 14.0 版本进行荟萃分析。本荟萃分析以 pf CRD42023392197.Result 的身份在 PROSPERO 数据库中注册:这项荟萃分析分析了 21,066 名接受过 VIA 检查的妇女的数据,以估算非洲的 VIA 阳性率。非洲 VIA 阳性的总体汇总效应估计值为 11.93(95%CI:11.48-12.37)。年龄 结论:与其他大洲相比,非洲 VIA 阳性的总体效应估计值较高。影响 VIA 阳性率的主要因素是首次性接触年龄在 16 岁以下、一生中至少有两个性伴侣以及 HIV 阳性。因此,世卫组织提出的在非洲消除宫颈癌的目标仍然需要付出巨大的努力。
期刊介绍:
Ethiopian Journal of Health Sciences is a general health science journal addressing clinical medicine, public health and biomedical sciences. Rarely, it covers veterinary medicine