Inhalational exposure history is associated with differential sinonasal gene expression profiles and clinical outcomes in chronic rhinosinusitis patients: A pilot study
Cameron P. Worden MD, Brian D. Thorp MD, Charles S. Ebert Jr. MD, MPH, Cristine N. Klatt-Cromwell MD, Brent A. Senior MD, Adam J. Kimple MD, PhD, Meghan E. Rebuli PhD, Ilona Jaspers PhD
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引用次数: 0
Abstract
Key points
Inhalational exposure (IE) history assessment is important and may guide chronic rhinosinusitis disease management.
Combined exposure status was the most significant factor across differential gene expression analyse
IE history was associated with pro-inflammatory transcriptome changes and worse clinical outcomes.
期刊介绍：
International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy.
International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.
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