A Narrative Review of Pain in Pediatric Oncology: The Opioid Option.

IF 3.4 3区 医学 Q1 PEDIATRICS Pediatric Drugs Pub Date : 2024-09-01 Epub Date: 2024-07-02 DOI:10.1007/s40272-024-00640-y
Elizabeth A Hall, Tracy M Hagemann, Chasity M Shelton, Hilary M Jasmin, Alexis N Calvasina, Doralina L Anghelescu
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Abstract

Opioid therapy is the mainstay for managing pain in pediatric oncology. This narrative review describes the current literature regarding opioids for pediatric cancer pain. The review explores the multifaceted landscape of opioid utilization in this population, including the role of opioids in certain clinical circumstances, modalities of opioid delivery, unique opioids, outpatient and at-home pain management strategies, and other key concepts such as breakthrough pain. This review highlights the importance of individualized dosing and multimodal approaches to enhance efficacy and minimize adverse effects. Drawing from a wide range of evidence, this review offers insights to optimize pediatric oncology pain management.

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儿科肿瘤疼痛的叙述性回顾:阿片类药物选择
阿片类药物治疗是儿科肿瘤疼痛治疗的主要手段。这篇叙述性综述介绍了目前有关阿片类药物治疗小儿癌痛的文献。综述探讨了该人群使用阿片类药物的多方面情况,包括阿片类药物在某些临床情况下的作用、阿片类药物的给药方式、独特的阿片类药物、门诊和居家疼痛管理策略以及突破性疼痛等其他关键概念。本综述强调了个体化剂量和多模式方法对提高疗效和减少不良反应的重要性。本综述借鉴了大量证据,为优化儿科肿瘤疼痛管理提供了真知灼见。
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来源期刊
Pediatric Drugs
Pediatric Drugs PEDIATRICS-PHARMACOLOGY & PHARMACY
CiteScore
7.20
自引率
0.00%
发文量
54
审稿时长
>12 weeks
期刊介绍: Pediatric Drugs promotes the optimization and advancement of all aspects of pharmacotherapy for healthcare professionals interested in pediatric drug therapy (including vaccines). The program of review and original research articles provides healthcare decision makers with clinically applicable knowledge on issues relevant to drug therapy in all areas of neonatology and the care of children and adolescents. The Journal includes: -overviews of contentious or emerging issues. -comprehensive narrative reviews of topics relating to the effective and safe management of drug therapy through all stages of pediatric development. -practical reviews covering optimum drug management of specific clinical situations. -systematic reviews that collate empirical evidence to answer a specific research question, using explicit, systematic methods as outlined by the PRISMA statement. -Adis Drug Reviews of the properties and place in therapy of both newer and established drugs in the pediatric population. -original research articles reporting the results of well-designed studies with a strong link to clinical practice, such as clinical pharmacodynamic and pharmacokinetic studies, clinical trials, meta-analyses, outcomes research, and pharmacoeconomic and pharmacoepidemiological studies. Additional digital features (including animated abstracts, video abstracts, slide decks, audio slides, instructional videos, infographics, podcasts and animations) can be published with articles; these are designed to increase the visibility, readership and educational value of the journal’s content. In addition, articles published in Pediatric Drugs may be accompanied by plain language summaries to assist readers who have some knowledge of, but not in-depth expertise in, the area to understand important medical advances.
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