Identification of Methamphetamine Abusers Can Be Supported by EEG-Based Wavelet Transform and BiLSTM Networks.

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-11-01 Epub Date: 2024-07-02 DOI:10.1007/s10548-024-01062-2
Hui Zhou, Jiaqi Zhang, Junfeng Gao, Xuanwei Zeng, Xiangde Min, Huimiao Zhan, Hua Zheng, Huaifei Hu, Yong Yang, Shuguang Wei
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Abstract

Methamphetamine (MA) is a neurological drug, which is harmful to the overall brain cognitive function when abused. Based on this property of MA, people can be divided into those with MA abuse and healthy people. However, few studies to date have investigated automatic detection of MA abusers based on the neural activity. For this reason, the purpose of this research was to investigate the difference in the neural activity between MA abusers and healthy persons and accordingly discriminate MA abusers. First, we performed event-related potential (ERP) analysis to determine the time range of P300. Then, the wavelet coefficients of the P300 component were extracted as the main features, along with the time and frequency domain features within the selected P300 range to classify. To optimize the feature set, F_score was used to remove features below the average score. Finally, a Bidirectional Long Short-term Memory (BiLSTM) network was performed for classification. The experimental result showed that the detection accuracy of BiLSTM could reach 83.85%. In conclusion, the P300 component of EEG signals of MA abusers is different from that in normal persons. Based on this difference, this study proposes a novel way for the prevention and diagnosis of MA abuse.

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基于脑电图的小波变换和 BiLSTM 网络可支持甲基苯丙胺滥用者的识别。
甲基苯丙胺(MA)是一种神经系统药物,滥用后对大脑的整体认知功能有害。根据甲基苯丙胺的这一特性,可将人分为滥用甲基苯丙胺者和健康人。然而,迄今为止,根据神经活动自动检测 MA 滥用者的研究还很少。因此,本研究旨在调查 MA 滥用者和健康人神经活动的差异,并据此判别 MA 滥用者。首先,我们进行了事件相关电位(ERP)分析,以确定 P300 的时间范围。然后,提取 P300 分量的小波系数作为主要特征,并在选定的 P300 范围内提取时域和频域特征进行分类。为了优化特征集,使用 F_score 去除低于平均分数的特征。最后,使用双向长短期记忆(BiLSTM)网络进行分类。实验结果表明,BiLSTM 的检测准确率可达 83.85%。总之,滥用精神药物者脑电信号中的 P300 分量与正常人不同。基于这种差异,本研究提出了一种预防和诊断 MA 滥用的新方法。
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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