Living in urban forests strengthens radical scavenging activity to delay aging: a pilot animal study

IF 2.6 2区 农林科学 Q1 FORESTRY European Journal of Forest Research Pub Date : 2024-06-29 DOI:10.1007/s10342-024-01708-7
Yanling Li, Xiaocong Li
{"title":"Living in urban forests strengthens radical scavenging activity to delay aging: a pilot animal study","authors":"Yanling Li, Xiaocong Li","doi":"10.1007/s10342-024-01708-7","DOIUrl":null,"url":null,"abstract":"<p>The aging process is influenced by the accumulation of both beneficial and harmful factors in the external environment. While extensive literature has explored the health benefits of short-term forest bathing, the potential for long-term exposure to forests to delay the aging process remains unclear. This study aimed to investigate the impact of prolonged urban forest contact on aging using a murine model. Forty male Specified Pathogen Free degree Kunming mice (6 weeks old, average weight 30.44 ± 0.91 g) were subjected to continuous subcutaneous injection of D-galactose in an urban environment and an urban forest environment to simulate an accelerated aging process lasting six weeks. Results showed that compared to urban environment, mice living in the forest environment exhibited significantly increased levels of serum oxidases CAT, GSH-Px, and SOD, as well as decreased levels of oxidative products H<sub>2</sub>O<sub>2</sub> and MDA. These findings suggest that long-term forest living enhances serum Nrf2 expression, downstream oxidase activity, total antioxidant capacity, and resistance to free radicals and oxidative products, thus delaying the aging process. This study offers valuable insights into the potential health benefits of long-term forest living, which may play a role in delaying the aging process in humans.</p>","PeriodicalId":11996,"journal":{"name":"European Journal of Forest Research","volume":"28 1","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Forest Research","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1007/s10342-024-01708-7","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"FORESTRY","Score":null,"Total":0}
引用次数: 0

Abstract

The aging process is influenced by the accumulation of both beneficial and harmful factors in the external environment. While extensive literature has explored the health benefits of short-term forest bathing, the potential for long-term exposure to forests to delay the aging process remains unclear. This study aimed to investigate the impact of prolonged urban forest contact on aging using a murine model. Forty male Specified Pathogen Free degree Kunming mice (6 weeks old, average weight 30.44 ± 0.91 g) were subjected to continuous subcutaneous injection of D-galactose in an urban environment and an urban forest environment to simulate an accelerated aging process lasting six weeks. Results showed that compared to urban environment, mice living in the forest environment exhibited significantly increased levels of serum oxidases CAT, GSH-Px, and SOD, as well as decreased levels of oxidative products H2O2 and MDA. These findings suggest that long-term forest living enhances serum Nrf2 expression, downstream oxidase activity, total antioxidant capacity, and resistance to free radicals and oxidative products, thus delaying the aging process. This study offers valuable insights into the potential health benefits of long-term forest living, which may play a role in delaying the aging process in humans.

Abstract Image

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
生活在城市森林中能增强自由基清除活性,从而延缓衰老:一项试验性动物研究
衰老过程受到外部环境中有益和有害因素积累的影响。虽然已有大量文献探讨了短期森林浴对健康的益处,但长期接触森林对延缓衰老过程的潜力仍不清楚。本研究旨在利用小鼠模型研究长期接触城市森林对衰老的影响。40只雄性无特定病原体昆明小鼠(6周龄,平均体重(30.44 ± 0.91)克)在城市环境和城市森林环境中连续皮下注射D-半乳糖,以模拟持续6周的加速衰老过程。结果表明,与城市环境相比,生活在森林环境中的小鼠血清氧化酶 CAT、GSH-Px 和 SOD 的水平明显升高,氧化产物 H2O2 和 MDA 的水平降低。这些发现表明,长期生活在森林中能增强血清中 Nrf2 的表达、下游氧化酶的活性、总抗氧化能力以及对自由基和氧化产物的抵抗力,从而延缓衰老过程。这项研究为长期森林生活的潜在健康益处提供了宝贵的见解,它可能在延缓人类衰老过程中发挥作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
CiteScore
5.10
自引率
3.60%
发文量
77
审稿时长
6-16 weeks
期刊介绍: The European Journal of Forest Research focuses on publishing innovative results of empirical or model-oriented studies which contribute to the development of broad principles underlying forest ecosystems, their functions and services. Papers which exclusively report methods, models, techniques or case studies are beyond the scope of the journal, while papers on studies at the molecular or cellular level will be considered where they address the relevance of their results to the understanding of ecosystem structure and function. Papers relating to forest operations and forest engineering will be considered if they are tailored within a forest ecosystem context.
期刊最新文献
Allometric equations for biomass and carbon pool estimation in short rotation Pinus radiata stands of the Western Cape, South Africa Effect of bedrock, tree size and time on growth and climate sensitivity of Norway spruce in the High Tatras Pure and mixed Scots pine forests showed divergent responses to climate variation and increased intrinsic water use efficiency across a European-wide climate gradient Preliminary validation of automated production analysis of feller buncher operations: integration of onboard computer data with LiDAR inventory Variability in fine root decomposition after forest thinning: effects of harvest intensity and root size
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1