Harnessing probiotic foods: managing cancer through gut health

IF 2.4 3区 农林科学 Q3 FOOD SCIENCE & TECHNOLOGY Food Science and Biotechnology Pub Date : 2024-06-28 DOI:10.1007/s10068-024-01638-5
Devika Thapa, Vijay Kumar, Bindu Naik, Vivek Kumar, Arun Kumar Gupta, Yugal Kishore Mohanta, Bishwambhar Mishra, Sarvesh Rustagi
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Abstract

One of the greatest threats to global health is cancer. Probiotic foods have been shown to have therapeutic promise in the management of cancer, even though traditional treatments such as radiation therapy, chemotherapy, and surgery are still essential. The generation of anticarcinogenic compounds, immune system stimulation, and gut microbiota regulation are a few ways that probiotics when taken in sufficient quantities, might help health. The purpose of this review is to examine the therapeutic potential of probiotic foods in the management of cancer. Research suggests that certain strains of probiotics have anticancer effects by preventing the growth of cancer cells, triggering apoptosis, and reducing angiogenesis in new tumors. Probiotics have shown promise in mitigating treatment-related adverse effects, such as diarrhea, mucositis, and immunosuppression caused by chemotherapy, improving the general quality of life for cancer patients. However, there are several factors, such as patient-specific features, cancer subtype, and probiotic strain type and dosage, which affect how effective probiotic therapies are in managing cancer. More research is necessary to find the long-term safety and efficacy characteristics of probiotics as well as to clarify the best ways to incorporate them into current cancer treatment methods.

Graphical abstract

Graphical representation showing the role of probiotic foods in cancer management.

Abstract Image

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利用益生菌食品:通过肠道健康控制癌症
癌症是全球健康面临的最大威胁之一。尽管放疗、化疗和手术等传统疗法仍然必不可少,但益生菌食品已被证明在癌症治疗方面具有治疗前景。产生抗癌化合物、刺激免疫系统和调节肠道微生物群是足量服用益生菌可能有助于健康的几种方式。本综述旨在探讨益生菌食品在治疗癌症方面的潜力。研究表明,某些益生菌株具有抗癌作用,能阻止癌细胞生长、引发细胞凋亡并减少新肿瘤的血管生成。益生菌在减轻化疗引起的腹泻、粘膜炎和免疫抑制等与治疗相关的不良反应方面显示出前景,可改善癌症患者的总体生活质量。然而,患者的具体特征、癌症亚型、益生菌菌株类型和剂量等多种因素都会影响益生菌疗法在控制癌症方面的效果。有必要开展更多研究,以确定益生菌的长期安全性和有效性特征,并明确将其纳入当前癌症治疗方法的最佳途径。
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来源期刊
Food Science and Biotechnology
Food Science and Biotechnology FOOD SCIENCE & TECHNOLOGY-
CiteScore
5.40
自引率
3.40%
发文量
174
审稿时长
2.3 months
期刊介绍: The FSB journal covers food chemistry and analysis for compositional and physiological activity changes, food hygiene and toxicology, food microbiology and biotechnology, and food engineering involved in during and after food processing through physical, chemical, and biological ways. Consumer perception and sensory evaluation on processed foods are accepted only when they are relevant to the laboratory research work. As a general rule, manuscripts dealing with analysis and efficacy of extracts from natural resources prior to the processing or without any related food processing may not be considered within the scope of the journal. The FSB journal does not deal with only local interest and a lack of significant scientific merit. The main scope of our journal is seeking for human health and wellness through constructive works and new findings in food science and biotechnology field.
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