Active block EX-CCII based electrical circuit for practical impedance data of OSCC

IF 1.2 4区工程技术 Q4 COMPUTER SCIENCE, HARDWARE & ARCHITECTURE Analog Integrated Circuits and Signal Processing Pub Date : 2024-07-02 DOI:10.1007/s10470-024-02273-0

Bidhanshel Singh Athokpam, Ashish Ranjan, Sumita Banerjee, Vivek Bhatt, Mamata Maisnam, Saikat Mukherjee

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Abstract

Oral Squamous Cell Carcinoma (OSCC) is the most common oral cancer, and its behavior can be analyzed using bio-impedance. A single dispersion Cole model is designed using active block Extra X Current Conveyor (EX-CCII), which generates the existing practical oral OSCC bio-impedance data. An experimental result of cancer bio-impedance in the 20 Hz to 5 MHz range is well modeled with an active block EX-CCII resistors (R \(_{\infty }\) and R₁) and fractional capacitor (C_α). The proposed design can serve as a step forward for designing a purposeful method for analyzing the behavior of oral cancer impedance without any practical data. The functionality of the proposed electrical circuit for OSCC is well verified through PSPICE simulation using both 0.25 μm CMOS TSMC Technology parameters and the macro model of EX-CCII. Simulation results agree well with experimental bio-impedance data.

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基于有源块 EX-CCII 的电路，用于 OSCC 的实际阻抗数据

口腔鳞状细胞癌（OSCC）是最常见的口腔癌，其行为可通过生物阻抗进行分析。利用有源块 Extra X Current Conveyor（EX-CCII）设计了一个单一色散 Cole 模型，生成了现有实用的口腔 OSCC 生物阻抗数据。利用有源块 EX-CCII 电阻器（R （_{\infty }\ ）和 R1）以及分数电容器（Cα）对 20 Hz 至 5 MHz 范围内癌症生物阻抗的实验结果进行了很好的建模。所提出的设计可以在没有任何实际数据的情况下，为设计有目的的分析口腔癌阻抗行为的方法迈出一步。通过使用 0.25 μm CMOS TSMC 技术参数和 EX-CCII 宏模型进行 PSPICE 仿真，很好地验证了针对 OSCC 的拟议电路的功能。仿真结果与生物阻抗实验数据十分吻合。

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来源期刊

Analog Integrated Circuits and Signal Processing 工程技术-工程：电子与电气

CiteScore

0.30

自引率

7.10%

发文量

141

审稿时长

7.3 months

期刊介绍： Analog Integrated Circuits and Signal Processing is an archival peer reviewed journal dedicated to the design and application of analog, radio frequency (RF), and mixed signal integrated circuits (ICs) as well as signal processing circuits and systems. It features both new research results and tutorial views and reflects the large volume of cutting-edge research activity in the worldwide field today. A partial list of topics includes analog and mixed signal interface circuits and systems; analog and RFIC design; data converters; active-RC, switched-capacitor, and continuous-time integrated filters; mixed analog/digital VLSI systems; wireless radio transceivers; clock and data recovery circuits; and high speed optoelectronic circuits and systems.