Mike Saunders, Amy Weaver, Rebecca Stretch, D Jeyaratnam, Mariyam Mirfenderesky, David Elliott, Charlotte Patterson, David Williams, Dervla Td Kenna, Jack Turton, Karen L Osman, Jane F Turton, Colin S Brown, Jwt Elston
{"title":"Outbreak of <i>Ralstonia pickettii</i> associated with contamination of saline products distributed internationally, the United Kingdom, 2024.","authors":"Mike Saunders, Amy Weaver, Rebecca Stretch, D Jeyaratnam, Mariyam Mirfenderesky, David Elliott, Charlotte Patterson, David Williams, Dervla Td Kenna, Jack Turton, Karen L Osman, Jane F Turton, Colin S Brown, Jwt Elston","doi":"10.2807/1560-7917.ES.2024.29.27.2400384","DOIUrl":null,"url":null,"abstract":"<p><p>We describe an outbreak of <i>Ralstonia pickettii</i> in the United Kingdom, with isolates genetically indistinguishable from a 2023 Australian outbreak linked to internationally distributed saline solutions. Confirmed cases (n = 3) had bacteraemia, clinically relevant infection, indwelling venous lines and frequent healthcare contact. Multi-stakeholder intervention was required including product recall and risk communications. We recommend a low threshold for investigating clusters of <i>Ralstonia</i> species and similar opportunistic pathogens, considering contaminated product sources. Effective mitigation requires multi-agency partnership and international collaboration.</p>","PeriodicalId":12161,"journal":{"name":"Eurosurveillance","volume":null,"pages":null},"PeriodicalIF":9.9000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11225263/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Eurosurveillance","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2807/1560-7917.ES.2024.29.27.2400384","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
We describe an outbreak of Ralstonia pickettii in the United Kingdom, with isolates genetically indistinguishable from a 2023 Australian outbreak linked to internationally distributed saline solutions. Confirmed cases (n = 3) had bacteraemia, clinically relevant infection, indwelling venous lines and frequent healthcare contact. Multi-stakeholder intervention was required including product recall and risk communications. We recommend a low threshold for investigating clusters of Ralstonia species and similar opportunistic pathogens, considering contaminated product sources. Effective mitigation requires multi-agency partnership and international collaboration.
期刊介绍:
Eurosurveillance is a European peer-reviewed journal focusing on the epidemiology, surveillance, prevention, and control of communicable diseases relevant to Europe.It is a weekly online journal, with 50 issues per year published on Thursdays. The journal includes short rapid communications, in-depth research articles, surveillance reports, reviews, and perspective papers. It excels in timely publication of authoritative papers on ongoing outbreaks or other public health events. Under special circumstances when current events need to be urgently communicated to readers for rapid public health action, e-alerts can be released outside of the regular publishing schedule. Additionally, topical compilations and special issues may be provided in PDF format.