Relationship between angiogenesis biomarker endocan and apolipoproteins in patients with acute myocardial infarction.

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-07-05 DOI:10.1080/14796678.2024.2365552

Mehdi Hassanpour, Reza Rahbarghazi, Aysa Rezabakhsh, Rasa Khodavirdilou, Akbar Darbin, Elmira Zolali, Nasser Safaei

引用次数: 0

Abstract

Aim: In the current study, serum levels of endocan in patients attended with ST-elevation myocardial infarction, as well as the possible correlation with apolipoprotein-A1 (APO-A1) and APO-B were investigated.Materials & methods: In 80 men, endocan, cTnI, APO-A1, and APO-B levels were measured. Finally, the correlation of endocan with APO-A1, APO-B, and APO-B/ APO-A1 ratio was assessed.Results: Significant changes in APO-A1, APO-B, endocan levels, and APO-B/APO-A1 ratio were found in acute myocardial infarction cases compared with the control arm (p < 0.05). In addition, our finding showed a significant correlation between APO-B and endocan levels, but not APO-A.Conclusion: High endocan level is an independent indicator of endothelial dysfunction and ischemic cardiovascular conditions, which could be related to APO-B.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

急性心肌梗死患者血管生成生物标志物内皮素与脂蛋白之间的关系

目的：本研究调查了ST段抬高型心肌梗死患者血清中的内切酶水平，以及与载脂蛋白-A1（APO-A1）和APO-B可能存在的相关性。材料与方法：在 80 名男性中测量内皮素、cTnI、APO-A1 和 APO-B 水平。最后，评估内切酶与 APO-A1、APO-B 和 APO-B/ APO-A1 比值的相关性。结果显示与对照组相比，急性心肌梗死病例的 APO-A1、APO-B、内切酶水平和 APO-B/APO-A1 比值均发生了显著变化（P 结论：内切酶水平高是心肌梗死的一个独立因素：内切酶水平高是内皮功能障碍和心血管缺血的独立指标，这可能与 APO-B 有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Future cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.80

自引率

5.90%

发文量

期刊介绍： Research advances have contributed to improved outcomes across all specialties, but the rate of advancement in cardiology has been exceptional. Concurrently, the population of patients with cardiac conditions continues to grow and greater public awareness has increased patients" expectations of new drugs and devices. Future Cardiology (ISSN 1479-6678) reflects this new era of cardiology and highlights the new molecular approach to advancing cardiovascular therapy. Coverage will also reflect the major technological advances in bioengineering in cardiology in terms of advanced and robust devices, miniaturization, imaging, system modeling and information management issues.