Sildenafil-induced drug reaction with eosinophilia and systemic symptoms

IF 0.5 Q4 UROLOGY & NEPHROLOGY Urology Case Reports Pub Date : 2024-07-01 DOI:10.1016/j.eucr.2024.102789
Amel Chabbouh , Faten Rebhi , Malek Ben Slimene , Kahena Jaber , Abderaouf Dhaoui
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引用次数: 0

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS)/drug-induced hypersensitivity syndrome (DIHS) is a life-threatening, multi-organ adverse drug reaction with a mortality rate of approximately 10 %–20 %. The most common culprit drugs are anticonvulsants, some antibiotics such as dapsone and minocycline, salazosulfapyridine, allopurinol and some antiretroviral molecules such as abacavir and nevirapine. Only one case of DRESS induced by sildenafil has been reported in the literature. Here we report a new case.

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西地那非引起的伴有嗜酸性粒细胞增多和全身症状的药物反应
伴有嗜酸性粒细胞增多和全身症状的药物反应(DRESS)/药物诱发超敏综合征(DIHS)是一种危及生命的多器官药物不良反应,死亡率约为 10%-20%。最常见的致病药物是抗惊厥药、某些抗生素(如达泊松和米诺环素)、柳氮磺吡啶、别嘌呤醇和某些抗逆转录病毒分子(如阿巴卡韦和奈韦拉平)。文献中仅报道过一例西地那非诱发的 DRESS。在此,我们报告了一例新病例。
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来源期刊
Urology Case Reports
Urology Case Reports Medicine-Urology
CiteScore
0.90
自引率
20.00%
发文量
325
审稿时长
37 days
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