This study reports a sporadic case of a 44-year-old male with congenital hypospadias complicated by a seminal vesicle cyst and accessory urethra. The patient presented with recurrent dysuria, and after undergoing laparoscopic seminal vesiculectomy combined with targeted anti-infective therapy, his symptoms were significantly relieved with favorable recovery. This case suggests that comprehensive imaging evaluation, individualized surgical planning, and long-term standardized follow-up are of great value in the diagnosis and treatment of such complex urinary system malformations.
{"title":"Congenital hypospadias complicated with pelvic cystic lesions and accessory urethra:A case report","authors":"Aersi Madanyeti , Zhangjie Zheng , Feng Tang , Jianping Peng","doi":"10.1016/j.eucr.2026.103357","DOIUrl":"10.1016/j.eucr.2026.103357","url":null,"abstract":"<div><div>This study reports a sporadic case of a 44-year-old male with congenital hypospadias complicated by a seminal vesicle cyst and accessory urethra. The patient presented with recurrent dysuria, and after undergoing laparoscopic seminal vesiculectomy combined with targeted anti-infective therapy, his symptoms were significantly relieved with favorable recovery. This case suggests that comprehensive imaging evaluation, individualized surgical planning, and long-term standardized follow-up are of great value in the diagnosis and treatment of such complex urinary system malformations.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103357"},"PeriodicalIF":0.4,"publicationDate":"2026-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-27DOI: 10.1016/j.eucr.2026.103362
Mahdi Hemmati Ghavshough, Melinda Z. Fu, Jennifer Sykes, Disha Patel, Saum Ghodoussipour, Vignesh T. Packiam
Non–muscle-invasive bladder cancer (NMIBC) with prostatic urethral involvement (PUI) is rare and difficult to manage, especially after intravesical therapy or pelvic radiation. We report a 78-year-old man with recurrent high-risk NMIBC and PUI after bacillus Calmette–Guérin and mitomycin C. Blue-light cystoscopy (BLC) during restaging identified additional carcinoma in situ and high-grade T1 disease not seen with white light. Histopathology showed no stromal invasion, and tumor-informed circulating tumor DNA (ctDNA) testing was negative, indicating no molecular residual disease. Despite favorable findings, the patient elected radical cystectomy, which revealed no residual tumor. This case highlights the complementary roles of BLC and ctDNA.
{"title":"Utility of blue-light cystoscopy and tumor-informed ctDNA for management of recurrent high-risk NMIBC with prostatic urethral involvement: A case report","authors":"Mahdi Hemmati Ghavshough, Melinda Z. Fu, Jennifer Sykes, Disha Patel, Saum Ghodoussipour, Vignesh T. Packiam","doi":"10.1016/j.eucr.2026.103362","DOIUrl":"10.1016/j.eucr.2026.103362","url":null,"abstract":"<div><div>Non–muscle-invasive bladder cancer (NMIBC) with prostatic urethral involvement (PUI) is rare and difficult to manage, especially after intravesical therapy or pelvic radiation. We report a 78-year-old man with recurrent high-risk NMIBC and PUI after bacillus Calmette–Guérin and mitomycin C. Blue-light cystoscopy (BLC) during restaging identified additional carcinoma in situ and high-grade T1 disease not seen with white light. Histopathology showed no stromal invasion, and tumor-informed circulating tumor DNA (ctDNA) testing was negative, indicating no molecular residual disease. Despite favorable findings, the patient elected radical cystectomy, which revealed no residual tumor. This case highlights the complementary roles of BLC and ctDNA.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103362"},"PeriodicalIF":0.4,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-27DOI: 10.1016/j.eucr.2026.103361
Michael Dagovetz , Melanie Fox , Suchit Patel , Monique Germain , Anthony Khuu , Eric Kim
Primary squamous cell carcinoma (PSCC) of the prostate is a rare, aggressive malignancy that presents diagnostic and therapeutic challenges. We present a unique case of PSCC arising from squamous metaplasia coexisting with a separate adenocarcinoma, forming a collision tumor. Dual-tracer imaging demonstrated distinct FDG and PSMA-avid metastases, reflecting independent biology. This case represents, to our knowledge, the first report of a true prostatic collision tumor with independent PSCC and adenocarcinoma, expanding the spectrum of prostate cancer variants.
{"title":"Primary squamous cell carcinoma of the prostate with coexisting separate adenocarcinoma: A case report and review of the literature","authors":"Michael Dagovetz , Melanie Fox , Suchit Patel , Monique Germain , Anthony Khuu , Eric Kim","doi":"10.1016/j.eucr.2026.103361","DOIUrl":"10.1016/j.eucr.2026.103361","url":null,"abstract":"<div><div>Primary squamous cell carcinoma (PSCC) of the prostate is a rare, aggressive malignancy that presents diagnostic and therapeutic challenges. We present a unique case of PSCC arising from squamous metaplasia coexisting with a separate adenocarcinoma, forming a collision tumor. Dual-tracer imaging demonstrated distinct FDG and PSMA-avid metastases, reflecting independent biology. This case represents, to our knowledge, the first report of a true prostatic collision tumor with independent PSCC and adenocarcinoma, expanding the spectrum of prostate cancer variants.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103361"},"PeriodicalIF":0.4,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-23DOI: 10.1016/j.eucr.2026.103352
Alhareth Baarimah , Nahid Osman , Ziyad Althobaiti , Mohammed Althobaiti , Bader Alzahrani , Ashraf Soliman
Extratesticular schwannoma (neurilemmoma) is an exceedingly rare benign paratesticular tumor, the diagnosis of which is usually challenging. We present the case of a 10-year-old boy presenting with a painless scrotal mass. Scrotal ultrasonography confirmed the extratesticular location but offered nonspecific findings. A definitive diagnosis was established via histopathology after complete surgical excision. This case highlights the need to include schwannoma in the differential diagnosis of pediatric paratesticular masses. To our knowledge, this is the third documented pediatric intrascrotal extratesticular schwannoma and involved the youngest patient reported in the literature.
{"title":"Intrascrotal extratesticular schwannoma in a 10-year-old boy: A case report of an extremely rare benign tumor","authors":"Alhareth Baarimah , Nahid Osman , Ziyad Althobaiti , Mohammed Althobaiti , Bader Alzahrani , Ashraf Soliman","doi":"10.1016/j.eucr.2026.103352","DOIUrl":"10.1016/j.eucr.2026.103352","url":null,"abstract":"<div><div>Extratesticular schwannoma (neurilemmoma) is an exceedingly rare benign paratesticular tumor, the diagnosis of which is usually challenging. We present the case of a 10-year-old boy presenting with a painless scrotal mass. Scrotal ultrasonography confirmed the extratesticular location but offered nonspecific findings. A definitive diagnosis was established via histopathology after complete surgical excision. This case highlights the need to include schwannoma in the differential diagnosis of pediatric paratesticular masses. To our knowledge, this is the third documented pediatric intrascrotal extratesticular schwannoma and involved the youngest patient reported in the literature.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103352"},"PeriodicalIF":0.4,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-23DOI: 10.1016/j.eucr.2026.103349
Bader N. Alqahtani , Omaya I. Banihani
This case report aimed to describe the clinical presentation and surgical management of a congenital anterior urethral diverticulum (CAUD) with parental consanguinity. A 4-year-old boy presented to our center, complaining of increasingly difficult urination for two days. His parents were Saudi cousins. A clean catch urine sample was positive for E. coli and was sensitive to Cefuroxime. A voiding cystourethrogram revealed a penile anterior urethral diverticulum. The penis was degloved, the cavity of the anterior urethral diverticulum was opened, the edges were excised, and the mouth of the diverticulum was closed. Consanguinity as a risk factor remains to be explored.
{"title":"A case report of congenital anterior urethral diverticulum: Is parental consanguinity a possible risk factor?","authors":"Bader N. Alqahtani , Omaya I. Banihani","doi":"10.1016/j.eucr.2026.103349","DOIUrl":"10.1016/j.eucr.2026.103349","url":null,"abstract":"<div><div>This case report aimed to describe the clinical presentation and surgical management of a congenital anterior urethral diverticulum (CAUD) with parental consanguinity. A 4-year-old boy presented to our center, complaining of increasingly difficult urination for two days. His parents were Saudi cousins. A clean catch urine sample was positive for <em>E. coli</em> and was sensitive to Cefuroxime. A voiding cystourethrogram revealed a penile anterior urethral diverticulum. The penis was degloved, the cavity of the anterior urethral diverticulum was opened, the edges were excised, and the mouth of the diverticulum was closed. Consanguinity as a risk factor remains to be explored.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103349"},"PeriodicalIF":0.4,"publicationDate":"2026-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-21DOI: 10.1016/j.eucr.2026.103355
Abdihamid Hassan Hilowle , Abdisalam Ismail Hassan , Nuradin Mohamed Nur , Abdikarin Ahmed Mohamed , Abdikarim Hussein Mohamed
Neonatal priapism is an exceptionally rare and usually benign condition, most commonly representing a non-ischemic (high-flow) state that resolves spontaneously. We report a 5-day-old Somali neonate who presented with a painless penile erection persisting for more than 48 hours. Physical examination revealed no penile discoloration, rigidity, or tenderness, and laboratory evaluation showed no hematological abnormalities. Doppler ultrasonography was unavailable; however, clinical findings were consistent with non-ischemic priapism. The infant was managed conservatively with close observation, resulting in complete spontaneous resolution without complications. This case highlights that careful clinical assessment and conservative management are sufficient, even in resource-limited settings.
{"title":"Idiopathic neonatal priapism in a 5-day-Old Somali neonate from a low-resource setting: A case report","authors":"Abdihamid Hassan Hilowle , Abdisalam Ismail Hassan , Nuradin Mohamed Nur , Abdikarin Ahmed Mohamed , Abdikarim Hussein Mohamed","doi":"10.1016/j.eucr.2026.103355","DOIUrl":"10.1016/j.eucr.2026.103355","url":null,"abstract":"<div><div>Neonatal priapism is an exceptionally rare and usually benign condition, most commonly representing a non-ischemic (high-flow) state that resolves spontaneously. We report a 5-day-old Somali neonate who presented with a painless penile erection persisting for more than 48 hours. Physical examination revealed no penile discoloration, rigidity, or tenderness, and <u>laboratory evaluation</u> showed no hematological abnormalities. Doppler ultrasonography was unavailable; however, clinical findings were consistent with non-ischemic priapism. The infant was managed conservatively with close observation, resulting in complete spontaneous resolution without complications. This case highlights that careful clinical assessment and conservative management are sufficient, even in resource-limited settings.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103355"},"PeriodicalIF":0.4,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-21DOI: 10.1016/j.eucr.2026.103354
Nicholas Nordin, Ronkino McCoy, Shimron Brown, Nikhil Gopal
A 35-year-old male with no prior medical or surgical history presented with clot retention. Cystoscopy revealed bloody efflux from the left ureteral orifice. Ureteroscopy showed clots within the left lower renal moiety. CT angiogram and renal angiography confirmed a renal arteriovenous malformation (AVM) that was successfully embolized. To our knowledge, this is the first reported case of a congenital renal AVM in a duplex collecting system. Prior cases of congenital renal AVM presenting with gross hematuria are reviewed. This is an unusual cause of gross hematuria in patients, which occasionally can be severe. Nonetheless, selective angioembolization provides excellent outcomes.
{"title":"Congenital Renal arteriovenous malformation: An unusual cause of clot retention – Case report and review of the literature","authors":"Nicholas Nordin, Ronkino McCoy, Shimron Brown, Nikhil Gopal","doi":"10.1016/j.eucr.2026.103354","DOIUrl":"10.1016/j.eucr.2026.103354","url":null,"abstract":"<div><div>A 35-year-old male with no prior medical or surgical history presented with clot retention. Cystoscopy revealed bloody efflux from the left ureteral orifice. Ureteroscopy showed clots within the left lower renal moiety. CT angiogram and renal angiography confirmed a renal arteriovenous malformation (AVM) that was successfully embolized. To our knowledge, this is the first reported case of a congenital renal AVM in a duplex collecting system. Prior cases of congenital renal AVM presenting with gross hematuria are reviewed. This is an unusual cause of gross hematuria in patients, which occasionally can be severe. Nonetheless, selective angioembolization provides excellent outcomes.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103354"},"PeriodicalIF":0.4,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with diverse clinical presentations. Acute abdomen is an exceptionally uncommon manifestation, typically reflecting tumor rupture. We report a 39-year-old male presenting with acute abdominal pain and a palpable left upper-quadrant mass. Imaging demonstrated a massive adrenal tumor (17.8 × 15.1 × 20.2cm). En-bloc resection with negative margins was achieved without rupture while preserving adjacent organs. Histopathology confirmed ACC. The patient remains disease-free 36 months postoperatively without adjuvant therapy. Acute abdomen can be the presenting symptom of ACC even without tumor rupture. Timely intervention can prevent possible impending rupture, enabling complete resection and favorable oncological outcomes.
{"title":"Massive non-functioning Adrenocortical carcinoma presenting as acute abdomen without rupture: A case report","authors":"Shady H.Y.B. Girgis , Ihab H.Y. Barsoum , Shady Elia Anis , Mostafa Elgamal , Hany Yassa","doi":"10.1016/j.eucr.2026.103350","DOIUrl":"10.1016/j.eucr.2026.103350","url":null,"abstract":"<div><div>Adrenocortical carcinoma (ACC) is a rare, aggressive malignancy with diverse clinical presentations. Acute abdomen is an exceptionally uncommon manifestation, typically reflecting tumor rupture. We report a 39-year-old male presenting with acute abdominal pain and a palpable left upper-quadrant mass. Imaging demonstrated a massive adrenal tumor (17.8 × 15.1 × 20.2cm). En-bloc resection with negative margins was achieved without rupture while preserving adjacent organs. Histopathology confirmed ACC. The patient remains disease-free 36 months postoperatively without adjuvant therapy. Acute abdomen can be the presenting symptom of ACC even without tumor rupture. Timely intervention can prevent possible impending rupture, enabling complete resection and favorable oncological outcomes.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103350"},"PeriodicalIF":0.4,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146078540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-19DOI: 10.1016/j.eucr.2026.103351
Mauricio S. Rodríguez-Mar , Jose Manuel Torres-Zazueta , Ricardo Fernández-Ferreira , Josué Farid Elías-Delgado , Luis A. Jiménez-López , Abel A. Ricardez-Espinosa , Mariana Hernández-Ramírez
Primary angiosarcoma of the kidney is extremely rare and aggressive cancer when it presents renal vein thrombus. This presentation confers poor prognosis, with limited therapeutic options. We present a case that began with anemia and macroscopic hematuria. At diagnosis, computed tomography (CT) showed thrombosis of the left renal vein, and a radical nephrectomy was performed. Histological examination revealed a carcinoma of the collecting ducts of Bellini, with immunohistochemistry positive for epithelioid angiosarcoma.
{"title":"Primary renal angiosarcoma with renal vein thrombus: Case report and Review of literature","authors":"Mauricio S. Rodríguez-Mar , Jose Manuel Torres-Zazueta , Ricardo Fernández-Ferreira , Josué Farid Elías-Delgado , Luis A. Jiménez-López , Abel A. Ricardez-Espinosa , Mariana Hernández-Ramírez","doi":"10.1016/j.eucr.2026.103351","DOIUrl":"10.1016/j.eucr.2026.103351","url":null,"abstract":"<div><div>Primary angiosarcoma of the kidney is extremely rare and aggressive cancer when it presents renal vein thrombus. This presentation confers poor prognosis, with limited therapeutic options. We present a case that began with anemia and macroscopic hematuria. At diagnosis, computed tomography (CT) showed thrombosis of the left renal vein, and a radical nephrectomy was performed. Histological examination revealed a carcinoma of the collecting ducts of Bellini, with immunohistochemistry positive for epithelioid angiosarcoma.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103351"},"PeriodicalIF":0.4,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-14DOI: 10.1016/j.eucr.2026.103346
Mohammad K. Khan
Pump erosion is a rare complication of penile prosthesis implantation that often requires explantation. We present a 43-year-old diabetic male who developed impending pump erosion with scrotal skin thinning over a functional prosthesis pump. Salvage was performed by excision of the fibrotic pseudo-capsule and relocation of the pump into the median raphe, combined with antibiotic and antifungal irrigation. The patient recovered uneventfully with excellent cosmetic and functional outcomes. This case highlights pseudo-capsule excision and median raphe repositioning as a safe, effective salvage option in selected patients without infection.
{"title":"Impending erosion of penile prosthesis pump: Salvage management with pseudo-capsule excision and median raphe repositioning – A case report","authors":"Mohammad K. Khan","doi":"10.1016/j.eucr.2026.103346","DOIUrl":"10.1016/j.eucr.2026.103346","url":null,"abstract":"<div><div>Pump erosion is a rare complication of penile prosthesis implantation that often requires explantation. We present a 43-year-old diabetic male who developed impending pump erosion with scrotal skin thinning over a functional prosthesis pump. Salvage was performed by excision of the fibrotic pseudo-capsule and relocation of the pump into the median raphe, combined with antibiotic and antifungal irrigation. The patient recovered uneventfully with excellent cosmetic and functional outcomes. This case highlights pseudo-capsule excision and median raphe repositioning as a safe, effective salvage option in selected patients without infection.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"65 ","pages":"Article 103346"},"PeriodicalIF":0.4,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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