Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102868
Anoushka Mullasseril , Anh B. Lam , Alekhya Mitta , Daniel Morton , Andrew McIntosh , Sanjay Patel , Theresa Thai , Anand Annan , Adanma Ayanambakkam
Renal cell carcinoma (RCC) is the seventh most common cancer in the United States; clear cell RCC (ccRCC) is the most common subtype. We report a case of spontaneous regression of metastatic ccRCC and discuss possible underlying mechanisms informed by a literature review. While regression of metastatic RCC has been described following nephrectomy or treatment of the primary tumor, spontaneous regression is rare. Postulated underlying causes include tumor necrosis and immune-mediated responses. Of 29 identified cases of spontaneous regression, only ours occurred after only a biopsy. Better understanding of the pathophysiology of spontaneous regression in RCC will improve its management.
{"title":"Spontaneous regression of metastatic clear cell renal cell carcinoma: A report of a rare case and a review of the literature","authors":"Anoushka Mullasseril , Anh B. Lam , Alekhya Mitta , Daniel Morton , Andrew McIntosh , Sanjay Patel , Theresa Thai , Anand Annan , Adanma Ayanambakkam","doi":"10.1016/j.eucr.2024.102868","DOIUrl":"10.1016/j.eucr.2024.102868","url":null,"abstract":"<div><div>Renal cell carcinoma (RCC) is the seventh most common cancer in the United States; clear cell RCC (ccRCC) is the most common subtype. We report a case of spontaneous regression of metastatic ccRCC and discuss possible underlying mechanisms informed by a literature review. While regression of metastatic RCC has been described following nephrectomy or treatment of the primary tumor, spontaneous regression is rare. Postulated underlying causes include tumor necrosis and immune-mediated responses. Of 29 identified cases of spontaneous regression, only ours occurred after only a biopsy. Better understanding of the pathophysiology of spontaneous regression in RCC will improve its management.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102868"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emphysematous pyelonephritis and emphysematous cystitis are intractable diseases. Eight cases of bilateral emphysematous pyelonephritis and emphysematous cystitis have been reported, but no treatment has been established. An 88-year-old female was admitted with traumatic subarachnoid hemorrhage, and on the fourth day of hospitalization, she developed fever and septic shock. A computed tomography scan revealed bilateral emphysematous pyelonephritis and emphysematous cystitis. The patient was treated with bilateral double-J stents and an indwelling urethral catheter. This is the first report of bilateral emphysematous pyelonephritis and emphysematous cystitis treated conservatively with drainage and an internal stent, which may be a treatment option.
{"title":"Complicated case of bilateral emphysematous pyelonephritis and emphysematous cystitis successfully treated with transurethral drainage and ureteral stents","authors":"Yoshihiro Kawaguchi , Yoshikado Miyagawa , Shigehisa Mizuta , Kosuke Ueda , Kiyoaki Nishihara , Makoto Nakiri , Tsukasa Igawa","doi":"10.1016/j.eucr.2024.102877","DOIUrl":"10.1016/j.eucr.2024.102877","url":null,"abstract":"<div><div>Emphysematous pyelonephritis and emphysematous cystitis are intractable diseases. Eight cases of bilateral emphysematous pyelonephritis and emphysematous cystitis have been reported, but no treatment has been established. An 88-year-old female was admitted with traumatic subarachnoid hemorrhage, and on the fourth day of hospitalization, she developed fever and septic shock. A computed tomography scan revealed bilateral emphysematous pyelonephritis and emphysematous cystitis. The patient was treated with bilateral double-J stents and an indwelling urethral catheter. This is the first report of bilateral emphysematous pyelonephritis and emphysematous cystitis treated conservatively with drainage and an internal stent, which may be a treatment option.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102877"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142586529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102876
Zamari Noori, Mohammad Jawid Nazari
Isolated renal tuberculosis is a rare form of extrapulmonary TB, especially in immunocompetent individuals. This case report details the diagnosis and management of a 14-year-old male who presented with massive hydronephrosis of unknown cause. Initial investigations, including urine cultures, were inconclusive. However, percutaneous nephrostomy provided a key diagnostic opportunity. This case highlights the importance of considering TB in the differential diagnosis of patients with unexplained urinary tract abnormalities, even in immunocompetent patients.
{"title":"Hydronephrosis secondary to isolated renal tuberculosis in an immunocompetent adolescent: “A case report”","authors":"Zamari Noori, Mohammad Jawid Nazari","doi":"10.1016/j.eucr.2024.102876","DOIUrl":"10.1016/j.eucr.2024.102876","url":null,"abstract":"<div><div>Isolated renal tuberculosis is a rare form of extrapulmonary TB, especially in immunocompetent individuals. This case report details the diagnosis and management of a 14-year-old male who presented with massive hydronephrosis of unknown cause. Initial investigations, including urine cultures, were inconclusive. However, percutaneous nephrostomy provided a key diagnostic opportunity. This case highlights the importance of considering TB in the differential diagnosis of patients with unexplained urinary tract abnormalities, even in immunocompetent patients.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102876"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102848
Henry Pramana, Jupiter Sibarani
Calculi in the urethra are uncommon, and urethral calculi causing urethrocutaneous fistula are extremely rare. A 56 years-old man with history of urine passage from his scrotal area for a month. During physical examination, we found a multiple fistula in scrotal area and revealed by the ultrasound. Abdominal x-ray suggests a vesicolithiasis and multiple urethrolithiasis. To date, there are 14 cases of giant urethral stone with and without urethrocutaneous fistula reported in literature worldwide for the last 14 years. It was related to patients that delayed to seek a medical attention from his symptoms.
尿道结石并不常见，而尿道结石导致尿道皮肤瘘则极为罕见。一名 56 岁的男子有一个月从阴囊部位排尿的病史。体格检查时，我们发现阴囊部位有多发性瘘管，超声波检查也显示了这一情况。腹部 X 光片显示膀胱结石和多发性尿道结石。迄今为止，在过去的 14 年中，全世界共有 14 例巨大尿道结石伴有或不伴有尿道皮肤瘘的文献报道。这与患者出现症状后迟迟不就医有关。
{"title":"A giant urethral stone with urethrocutaneous fistula: A case report","authors":"Henry Pramana, Jupiter Sibarani","doi":"10.1016/j.eucr.2024.102848","DOIUrl":"10.1016/j.eucr.2024.102848","url":null,"abstract":"<div><div>Calculi in the urethra are uncommon, and urethral calculi causing urethrocutaneous fistula are extremely rare. A 56 years-old man with history of urine passage from his scrotal area for a month. During physical examination, we found a multiple fistula in scrotal area and revealed by the ultrasound. Abdominal x-ray suggests a vesicolithiasis and multiple urethrolithiasis. To date, there are 14 cases of giant urethral stone with and without urethrocutaneous fistula reported in literature worldwide for the last 14 years. It was related to patients that delayed to seek a medical attention from his symptoms.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102848"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102875
Gregory Palmateer , Edouard H. Nicaise , Jatin Gandhi , Taylor Goodstein , Michelle Sheng , Kenneth Ogan , Omer Kucuk , Melinda Yushak , Martin G. Sanda , Keith A. Delman , Viraj Master
Extramammary Paget disease (EMPD) is a rare dermatologic malignancy with a high rate of recurrence and increased risk for developing secondary malignancies. We present a 74-year-old male with previously resected primary EMPD who presented with widespread PSMA-avid lesions without prostatic uptake, an elevated PSA >100, and a negative prostate biopsy. Based on this and immunohistological staining, recurrent EMPD was suspected. However, after additional staining and reexamining their clinical presentation, metastatic prostate cancer without a detected primary lesion is more probable. This case highlights the diagnostic challenge variable expression of shared biomarkers found in EMPD and prostate cancer present to clinicians.
{"title":"The diagnostic challenges of differentiating metastatic extramammary Paget disease and prostatic adenocarcinoma: A case report and review of the literature","authors":"Gregory Palmateer , Edouard H. Nicaise , Jatin Gandhi , Taylor Goodstein , Michelle Sheng , Kenneth Ogan , Omer Kucuk , Melinda Yushak , Martin G. Sanda , Keith A. Delman , Viraj Master","doi":"10.1016/j.eucr.2024.102875","DOIUrl":"10.1016/j.eucr.2024.102875","url":null,"abstract":"<div><div>Extramammary Paget disease (EMPD) is a rare dermatologic malignancy with a high rate of recurrence and increased risk for developing secondary malignancies. We present a 74-year-old male with previously resected primary EMPD who presented with widespread PSMA-avid lesions without prostatic uptake, an elevated PSA >100, and a negative prostate biopsy. Based on this and immunohistological staining, recurrent EMPD was suspected. However, after additional staining and reexamining their clinical presentation, metastatic prostate cancer without a detected primary lesion is more probable. This case highlights the diagnostic challenge variable expression of shared biomarkers found in EMPD and prostate cancer present to clinicians.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102875"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142572260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102878
Randy Casals, Tyler Overholt, Steve Hodges, Marc Colaco
Circumcision is a common procedure performed since ancient times with an excellent safety profile and potential health benefits. In the United States, it is commonly performed in the neonatal period using devices such as the Gomco, Mogen, or Plastibell device. In the rare circumstance of a complication, it is often related to bleeding and usually managed conservatively. However, complications requiring surgical intervention can occur and remind practitioners of the importance of proper equipment and technique. Herein, we report a case in which extensive injuries to the penile skin after neonatal circumcision using a Gomco clamp required emergent intervention.
{"title":"Surgical repair of extensive penile shaft skin injuries following neonatal circumcision","authors":"Randy Casals, Tyler Overholt, Steve Hodges, Marc Colaco","doi":"10.1016/j.eucr.2024.102878","DOIUrl":"10.1016/j.eucr.2024.102878","url":null,"abstract":"<div><div>Circumcision is a common procedure performed since ancient times with an excellent safety profile and potential health benefits. In the United States, it is commonly performed in the neonatal period using devices such as the Gomco, Mogen, or Plastibell device. In the rare circumstance of a complication, it is often related to bleeding and usually managed conservatively. However, complications requiring surgical intervention can occur and remind practitioners of the importance of proper equipment and technique. Herein, we report a case in which extensive injuries to the penile skin after neonatal circumcision using a Gomco clamp required emergent intervention.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102878"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142592944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noncontrast computed tomography(CT) is commonly recommended for the diagnosis of suspected renal stones. In this paper, we present a case of a renal stone that cannot be detected by CT. The stone was made of n-butyl α-cyanoacrylate, a kind of surgical adhesives commonly used in partial nephrotomy.
{"title":"Undetectable renal stone on computed tomography","authors":"Guanghan Zhang , Zhicong Huang , Shaoying Li , Guohua Zeng , Wei Zhu","doi":"10.1016/j.eucr.2024.102873","DOIUrl":"10.1016/j.eucr.2024.102873","url":null,"abstract":"<div><div>Noncontrast computed tomography(CT) is commonly recommended for the diagnosis of suspected renal stones. In this paper, we present a case of a renal stone that cannot be detected by CT. The stone was made of n-butyl α-cyanoacrylate, a kind of surgical adhesives commonly used in partial nephrotomy.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102873"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102872
Madeleine Bain, Simon Pridgeon
Melioidosis infecting a periurethral diverticulum and behaving as an abscess is a rare complication. A 76-year-old woman presented with pelvic pain, dysuria and urinary frequency. CT identified a large periurethral cystic collection and melioidosis was cultured in her urine. Cystoscopy revealed communication between urethra and diverticulum, requiring multiple transvaginal aspirations for re-accumulation and relapsing symptoms. No risk factors for melioidosis were identified, and was likely that isolated urinary infection is due to her urinary tract pathology. This challenging case with a rare pathogen highlights management and source control of melioidosis may need to adapt to anatomical variations promoting abscess reformation.
{"title":"A rare case of an infected urethral diverticulum due to urinary melioidosis","authors":"Madeleine Bain, Simon Pridgeon","doi":"10.1016/j.eucr.2024.102872","DOIUrl":"10.1016/j.eucr.2024.102872","url":null,"abstract":"<div><div>Melioidosis infecting a periurethral diverticulum and behaving as an abscess is a rare complication. A 76-year-old woman presented with pelvic pain, dysuria and urinary frequency. CT identified a large periurethral cystic collection and melioidosis was cultured in her urine. Cystoscopy revealed communication between urethra and diverticulum, requiring multiple transvaginal aspirations for re-accumulation and relapsing symptoms. No risk factors for melioidosis were identified, and was likely that isolated urinary infection is due to her urinary tract pathology. This challenging case with a rare pathogen highlights management and source control of melioidosis may need to adapt to anatomical variations promoting abscess reformation.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102872"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102879
Marie-Lisa Eich , Kira Furlano , Georg Hilfenhaus , Bernhard Ralla , Ulrich Keilholz , Maria Joosten , Damian T. Rieke , Thorsten Schlomm , David Horst , Simon Schallenberg
We present the rare case of a 51-year-old male diagnosed with a solitary fibrous tumor (SFT) of the prostate, along with a concurrent low-grade prostate adenocarcinoma (Gleason score 3 + 3, Grade Group 1). The diagnosis was confirmed by positive immunohistochemical markers, including CD34, BCL2, and STAT6, and molecular analysis showing a NAB2-STAT6 fusion. Following successful surgical management and the simultaneous diagnosis of a pulmonary relapse from a prior thyroid carcinoma, the patient remains under clinical surveillance. This is particularly significant given the patient's history of multiple tumors, including Hodgkin's lymphoma, papillary thyroid carcinoma, prostate cancer, and SFT.
{"title":"Solitary fibrous tumor of the prostate with accompanying low-grade prostate cancer","authors":"Marie-Lisa Eich , Kira Furlano , Georg Hilfenhaus , Bernhard Ralla , Ulrich Keilholz , Maria Joosten , Damian T. Rieke , Thorsten Schlomm , David Horst , Simon Schallenberg","doi":"10.1016/j.eucr.2024.102879","DOIUrl":"10.1016/j.eucr.2024.102879","url":null,"abstract":"<div><div>We present the rare case of a 51-year-old male diagnosed with a solitary fibrous tumor (SFT) of the prostate, along with a concurrent low-grade prostate adenocarcinoma (Gleason score 3 + 3, Grade Group 1). The diagnosis was confirmed by positive immunohistochemical markers, including CD34, BCL2, and STAT6, and molecular analysis showing a NAB2-STAT6 fusion. Following successful surgical management and the simultaneous diagnosis of a pulmonary relapse from a prior thyroid carcinoma, the patient remains under clinical surveillance. This is particularly significant given the patient's history of multiple tumors, including Hodgkin's lymphoma, papillary thyroid carcinoma, prostate cancer, and SFT.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102879"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01DOI: 10.1016/j.eucr.2024.102881
Ketty Bai, Niccola B. Lynch, Christina P. Carpenter
Prostatic cysts are common in the adult male population with intervention of these cysts typically reserved for symptomatic patients. However, current literature is limited on the diagnosis and management of prostatic cysts in the pediatric population. We report the case of a 13-year-old boy with autosomal recessive polycystic kidney disease (ARPKD) who presented with an incidentally discovered prostatic cyst. This is the first known case report to highlight the clinical presentation, diagnosis, and management of an asymptomatic prostatic cyst in ARPKD.
{"title":"Prostatic cyst in autosomal recessive polycystic kidney disease: A case presentation and literature review","authors":"Ketty Bai, Niccola B. Lynch, Christina P. Carpenter","doi":"10.1016/j.eucr.2024.102881","DOIUrl":"10.1016/j.eucr.2024.102881","url":null,"abstract":"<div><div>Prostatic cysts are common in the adult male population with intervention of these cysts typically reserved for symptomatic patients. However, current literature is limited on the diagnosis and management of prostatic cysts in the pediatric population. We report the case of a 13-year-old boy with autosomal recessive polycystic kidney disease (ARPKD) who presented with an incidentally discovered prostatic cyst. This is the first known case report to highlight the clinical presentation, diagnosis, and management of an asymptomatic prostatic cyst in ARPKD.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"57 ","pages":"Article 102881"},"PeriodicalIF":0.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142663290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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