Correction to “Constitutive alpha-secretase cleavage of the beta-amyloid precursor protein in the furin-deficient LoVo cell line: involvement of the pro-hormone convertase 7 and the disintegrin and metalloprotease ADAM10”

Abstract

Lopez-Perez, E., Zhang, Y., Frank, S.J., Creemers, J., Seidah, N. and Checler, F. (2001), Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: Involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10. Journal of Neurochemistry, 76, 1532–1539. https://doi.org/10.1046/j.1471-4159.2001.00180.x

It came to our attention that “Fig. 5c M Control” is the same as “Fig. 5g M Control” and “Fig. 5c M TAPI” is the same as “Fig. 5g M TAPI”—they appear to be duplicates. In this set of experiments, mock, ADAM10 and TACE transfection experiments were always done in parallel and charged on the same gel. Thus, the mock-transfected cells (either control or TAPI-treated) are the common control for both ADAM10- and TACE-transfected cells. When separating data for ADAM10 or TACE1 for clarity purpose in 5c and 5g, illustrations were rearranged and the mock-transfected M +/− TAPI lanes were common for the two experimental conditions. This is illustrated by the identical bar graphs in 5d and 5h for mock-transfected (black bars) cells in control and TAPI conditions. This quantification supports the fact that we rearranged the gel by splitting it in two although keeping common control and TAPI mock-transfected conditions. The authors apologize for not providing this explanation when submitting the article.