Cartilage compositional MRI-a narrative review of technical development and clinical applications over the past three decades.

IF 1.9 3区 医学 Q2 ORTHOPEDICS Skeletal Radiology Pub Date : 2024-09-01 Epub Date: 2024-07-09 DOI:10.1007/s00256-024-04734-z
Xiaojuan Li, Jeehun Kim, Mingrui Yang, Ahmet H Ok, Štefan Zbýň, Thomas M Link, Sharmilar Majumdar, C Benjamin Ma, Kurt P Spindler, Carl S Winalski
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Abstract

Articular cartilage damage and degeneration are among hallmark manifestations of joint injuries and arthritis, classically osteoarthritis. Cartilage compositional MRI (Cart-C MRI), a quantitative technique, which aims to detect early-stage cartilage matrix changes that precede macroscopic alterations, began development in the 1990s. However, despite the significant advancements over the past three decades, Cart-C MRI remains predominantly a research tool, hindered by various technical and clinical hurdles. This paper will review the technical evolution of Cart-C MRI, delve into its clinical applications, and conclude by identifying the existing gaps and challenges that need to be addressed to enable even broader clinical application of Cart-C MRI.

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软骨成分核磁共振成像--对过去三十年技术发展和临床应用的回顾。
关节软骨损伤和退化是关节损伤和关节炎(主要是骨关节炎)的标志性表现之一。软骨成分核磁共振成像(Cart-C MRI)是一种定量技术,旨在检测软骨基质在发生宏观改变之前的早期变化。然而,尽管在过去三十年中取得了重大进展,Cart-C MRI 仍主要是一种研究工具,受到各种技术和临床障碍的阻碍。本文将回顾 Cart-C 核磁共振成像的技术演变,深入探讨其临床应用,最后指出现有的差距和需要解决的挑战,以实现 Cart-C 核磁共振成像更广泛的临床应用。
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来源期刊
Skeletal Radiology
Skeletal Radiology 医学-核医学
CiteScore
4.40
自引率
9.50%
发文量
253
审稿时长
3-8 weeks
期刊介绍: Skeletal Radiology provides a forum for the dissemination of current knowledge and information dealing with disorders of the musculoskeletal system including the spine. While emphasizing the radiological aspects of the many varied skeletal abnormalities, the journal also adopts an interdisciplinary approach, reflecting the membership of the International Skeletal Society. Thus, the anatomical, pathological, physiological, clinical, metabolic and epidemiological aspects of the many entities affecting the skeleton receive appropriate consideration. This is the Journal of the International Skeletal Society and the Official Journal of the Society of Skeletal Radiology and the Australasian Musculoskelelal Imaging Group.
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