Emerging and extensive clonal evolution in the pancreas.

IF 14.3 1区 医学 Q1 ONCOLOGY Trends in cancer Pub Date : 2024-08-01 Epub Date: 2024-07-07 DOI:10.1016/j.trecan.2024.06.011
Alvin P Makohon-Moore
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引用次数: 0

Abstract

Pancreatic cancer is one of the most lethal malignancies, yet much remains to be learned regarding how its precursors develop. In a recent Nature publication, Braxton and Kiemen et al. found that the normal, adult pancreas harbors hundreds to thousands of pancreatic cancer precursors evolving by a variety of routes.

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胰腺新出现的广泛克隆进化。
胰腺癌是最致命的恶性肿瘤之一,但关于它的前体是如何发育的,还有很多知识有待了解。在最近发表的《自然》杂志上,Braxton 和 Kiemen 等人发现,正常的成人胰腺中蕴藏着成百上千的胰腺癌前体,它们通过各种途径进化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Trends in cancer
Trends in cancer Medicine-Oncology
CiteScore
28.50
自引率
0.50%
发文量
138
期刊介绍: Trends in Cancer, a part of the Trends review journals, delivers concise and engaging expert commentary on key research topics and cutting-edge advances in cancer discovery and medicine. Trends in Cancer serves as a unique platform for multidisciplinary information, fostering discussion and education for scientists, clinicians, policy makers, and patients & advocates.Covering various aspects, it presents opportunities, challenges, and impacts of basic, translational, and clinical findings, industry R&D, technology, innovation, ethics, and cancer policy and funding in an authoritative yet reader-friendly format.
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