Fatemeh Doraghi, Azam Serajian, Somaye Karimian, Bagher Larijani, Mohammad Mahdavi
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引用次数: 0
Abstract
Pyridinium salts have been used as starting materials and intermediates in 1,3-dipolar cycloaddition with dipolarophiles. Among them, N-phenacylpyridinium salts can easily react with dipolarophiles due to having a good electron-attracting COPh group. This group can stabilize pyridinium ylide generated in situ from N-phenacylpyridinium salts. The synthesis of a wide variety of biologically active N-, O-, and S-heterocycles, as well as carbocycles, can be achieved from N-phenacylpyridinium salt precursors. This review highlights important cyclization and functionalization reactions, involving N-phenacylpyridinium salts.
Graphical abstract
N-phenacylpyridinium salts, an important subclass of pyridinium salts, serve as an intermediate, as well as a starting material in the synthesis of a diverse range of N-, O-, and S-heterocycles, as well as carbocycles. The construction of important biologically active molecules, such as indolizine, pyridine, quinoline, pyrrole, azepine, dihydrofuran, and chromene, can be achieved from N-phenacylpyridinium salt precursors. This review highlights cyclization and functionalization reactions, involving N-phenacylpyridinium salts.
Chemical PapersChemical Engineering-General Chemical Engineering
CiteScore
3.30
自引率
4.50%
发文量
590
期刊介绍:
Chemical Papers is a peer-reviewed, international journal devoted to basic and applied chemical research. It has a broad scope covering the chemical sciences, but favors interdisciplinary research and studies that bring chemistry together with other disciplines.