Synthesis of three-component bioactive glass SiO2– CaO– P2O5 by hydrothermal method using oleic acid as a surfactant

Abstract

This work presents the synthesis of bioactive glass 55SiO₂– 41CaO– 4P₂O₅ (mol%) by the hydrothermal method using oleic acid as a structural-control agent. Glass samples synthesized at different oleic acid concentrations 0 M, 0.25 M, 0.5 M, and 1 M (denoted as 55 S-0 M, 55 S-0.25 M, 55 S-0.5 M, 55 S-1 M) were characterized by physic-chemical methods such as TGA-DCS, XRD, FTIR, SEM, TEM, and BET. According to the findings, glass materials in the form of amorphous and mesoporous structures can be synthesized by heating dried gel at about 700 ^oC. The formation of sharp hydroxyapatite peaks after in vitro experiment shows higher bioactivity in samples 55 S-0.25 M, and 55 S-0.5 M, which have higher porosity, and specific surface area. Furthermore, all glass samples synthesized in oleic acid demonstrate excellent biocompatibility with fibroblast cells (L-929).