A mathematical model for a disease outbreak considering waning-immunity class with nonlinear incidence and recovery rates

Q1 Social Sciences Journal of Biosafety and Biosecurity Pub Date : 2024-06-26 DOI:10.1016/j.jobb.2024.05.005
Nursanti Anggriani , Lazarus Kalvein Beay , Meksianis Z. Ndii , Fatuh Inayaturohmat , Sanubari Tansah Tresna
{"title":"A mathematical model for a disease outbreak considering waning-immunity class with nonlinear incidence and recovery rates","authors":"Nursanti Anggriani ,&nbsp;Lazarus Kalvein Beay ,&nbsp;Meksianis Z. Ndii ,&nbsp;Fatuh Inayaturohmat ,&nbsp;Sanubari Tansah Tresna","doi":"10.1016/j.jobb.2024.05.005","DOIUrl":null,"url":null,"abstract":"<div><p>In the spread of infectious diseases, intervention levels play a crucial role in shaping interactions between healthy and infected individuals, leading to a nonlinear transmission process. Additionally, the availability of medical resources limits the recovery rate of infected patients, adding further nonlinear dynamics to the healing process. Our research introduces novelty by combining nonlinear incidence and recovery rates alongside waning immunity in an epidemic model. We present a modified SIRW-type model, examining the epidemic problem with these factors. Through analysis, we explore conditions for non-endemic and co-existing cases based on the basic reproduction ratio. The local stability of equilibria is verified using the Routh-Hurwitz criteria, while global stability is assessed using Lyapunov functions for each equilibrium. Furthermore, we investigate bifurcations around both non-endemic and co-existing equilibria. Numerically, we give some simulations to support our analytical findings.</p></div>","PeriodicalId":52875,"journal":{"name":"Journal of Biosafety and Biosecurity","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2588933824000311/pdfft?md5=9a3f3ac37c5d275226798d8df28d62fc&pid=1-s2.0-S2588933824000311-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biosafety and Biosecurity","FirstCategoryId":"1093","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2588933824000311","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Social Sciences","Score":null,"Total":0}
引用次数: 0

Abstract

In the spread of infectious diseases, intervention levels play a crucial role in shaping interactions between healthy and infected individuals, leading to a nonlinear transmission process. Additionally, the availability of medical resources limits the recovery rate of infected patients, adding further nonlinear dynamics to the healing process. Our research introduces novelty by combining nonlinear incidence and recovery rates alongside waning immunity in an epidemic model. We present a modified SIRW-type model, examining the epidemic problem with these factors. Through analysis, we explore conditions for non-endemic and co-existing cases based on the basic reproduction ratio. The local stability of equilibria is verified using the Routh-Hurwitz criteria, while global stability is assessed using Lyapunov functions for each equilibrium. Furthermore, we investigate bifurcations around both non-endemic and co-existing equilibria. Numerically, we give some simulations to support our analytical findings.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
考虑到非线性发病率和恢复率的免疫力减弱类疾病爆发数学模型
在传染病的传播过程中,干预水平对健康人和受感染者之间的互动起着至关重要的作用,从而导致非线性传播过程。此外,医疗资源的可用性也限制了感染者的康复率,进一步增加了治疗过程的非线性动态性。我们的研究将非线性发病率和康复率与免疫力减弱结合在一个流行病模型中,从而带来了新颖性。我们提出了一个改进的 SIRW 型模型,研究了包含这些因素的流行病问题。通过分析,我们探讨了基于基本繁殖率的非流行病例和共存病例的条件。我们使用 Routh-Hurwitz 准则验证了均衡的局部稳定性,同时使用每个均衡的 Lyapunov 函数评估了全局稳定性。此外,我们还研究了非地方性均衡和共存均衡周围的分岔。在数值上,我们给出了一些模拟来支持我们的分析结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Journal of Biosafety and Biosecurity
Journal of Biosafety and Biosecurity Social Sciences-Linguistics and Language
CiteScore
6.00
自引率
0.00%
发文量
20
审稿时长
41 days
期刊最新文献
Genetic diversity, virulence profiles, and antimicrobial resistance of Salmonella enterica serovar Typhi isolated from typhoid fever patients in Baghdad, Iraq Pseudovirus technology in global health: A critical need for robust biosecurity measures Computational modeling and inhibition of SARS-COV-2 Papain-like protease enzyme: A potential therapeutic approach for COVID-19 Exploring the Interplay Between Social Awareness and the Use of Bed Nets in a Malaria Control Program Modeling and optimal control of COVID-19 with comorbidity and three-dose vaccination in Indonesia
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1