loco-pipe: an automated pipeline for population genomics with low-coverage whole-genome sequencing.

IF 2.4 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY Bioinformatics advances Pub Date : 2024-07-11 eCollection Date: 2024-01-01 DOI:10.1093/bioadv/vbae098
Zehua T Zhou, Gregory L Owens, Wesley A Larson, Runyang Nicolas Lou, Peter H Sudmant
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Abstract

Summary: We developed loco-pipe, a Snakemake pipeline that seamlessly streamlines a set of essential population genomic analyses for low-coverage whole genome sequencing (lcWGS) data. loco-pipe is highly automated, easily customizable, massively parallelized, and thus is a valuable tool for both new and experienced users of lcWGS.

Availability and implementation: loco-pipe is published under the GPLv3. It is freely available on GitHub (github.com/sudmantlab/loco-pipe) and archived on Zenodo (doi.org/10.5281/zenodo.10425920).

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loco-pipe:利用低覆盖率全基因组测序进行群体基因组学研究的自动化管道。
摘要:我们开发了一个Snakemake管道--loco-pipe,它可以无缝简化低覆盖率全基因组测序(lcWGS)数据的一系列基本群体基因组分析。loco-pipe高度自动化、易于定制、大规模并行化,因此对于lcWGS的新用户和有经验的用户来说都是一个有价值的工具。它可在 GitHub(github.com/sudmantlab/loco-pipe)上免费获取,并在 Zenodo(doi.org/10.5281/zenodo.10425920)上存档。
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