{"title":"Phthalates released from microplastics can't be ignored: Sources, fate, ecological risks, and human exposure risks","authors":"","doi":"10.1016/j.trac.2024.117870","DOIUrl":null,"url":null,"abstract":"<div><p>Phthalates are widely used as plasticizers in plastic production. Due to the absence of covalent bonds with plastic polymers, phthalates can continuously leach from the plastics into the environment. As the ocean is the largest sink for microplastics, large amounts of phthalates could be released into the marine environment along with microplastics. Besides their migration and transformation in the marine environment, phthalates could be accumulated in organisms and exhibit endocrine-disrupting effects. This review summarizes the leaching mechanisms and influencing factors of phthalates from microplastics, the migration and transformation of phthalates in different media, and the environmental degradation processes. The toxic effects of phthalates and their ecological risks to marine ecosystems are outlined. Furthermore, human exposure risks to phthalates based on the levels of phthalate metabolites in urine worldwide are evaluated. Future research on phthalate-microplastics interactions, toxicity of mixed phthalates, and conjugated metabolites are highly warranted.</p></div>","PeriodicalId":439,"journal":{"name":"Trends in Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":11.8000,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in Analytical Chemistry","FirstCategoryId":"1","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165993624003534","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Phthalates are widely used as plasticizers in plastic production. Due to the absence of covalent bonds with plastic polymers, phthalates can continuously leach from the plastics into the environment. As the ocean is the largest sink for microplastics, large amounts of phthalates could be released into the marine environment along with microplastics. Besides their migration and transformation in the marine environment, phthalates could be accumulated in organisms and exhibit endocrine-disrupting effects. This review summarizes the leaching mechanisms and influencing factors of phthalates from microplastics, the migration and transformation of phthalates in different media, and the environmental degradation processes. The toxic effects of phthalates and their ecological risks to marine ecosystems are outlined. Furthermore, human exposure risks to phthalates based on the levels of phthalate metabolites in urine worldwide are evaluated. Future research on phthalate-microplastics interactions, toxicity of mixed phthalates, and conjugated metabolites are highly warranted.
期刊介绍:
TrAC publishes succinct and critical overviews of recent advancements in analytical chemistry, designed to assist analytical chemists and other users of analytical techniques. These reviews offer excellent, up-to-date, and timely coverage of various topics within analytical chemistry. Encompassing areas such as analytical instrumentation, biomedical analysis, biomolecular analysis, biosensors, chemical analysis, chemometrics, clinical chemistry, drug discovery, environmental analysis and monitoring, food analysis, forensic science, laboratory automation, materials science, metabolomics, pesticide-residue analysis, pharmaceutical analysis, proteomics, surface science, and water analysis and monitoring, these critical reviews provide comprehensive insights for practitioners in the field.