{"title":"Future directions in flow biocatalysis: The impact of new technology on sustainability","authors":"Rebecca E. Ruscoe, Sebastian C. Cosgrove","doi":"10.1016/j.cogsc.2024.100954","DOIUrl":null,"url":null,"abstract":"<div><p>Flow chemistry is now a key technology for synthetic chemistry, with the different operating windows available allowing new chemistry to be optimised and discovered. The related area of flow biocatalysis is also becoming increasingly recognised as an integral aspect of bioprocess optimisation, with modularisation and technology integration some of the key drivers for this. This minireview will discuss some recent examples where flow has substantially improved the sustainability of a bioprocess. We also reflect on the increase in analytics, how it is starting to impact bioprocess optimisation, and what the implications of this will be moving forward.</p></div>","PeriodicalId":54228,"journal":{"name":"Current Opinion in Green and Sustainable Chemistry","volume":"49 ","pages":"Article 100954"},"PeriodicalIF":9.3000,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2452223624000750/pdfft?md5=feadc175fd49d0f13361a96f5514a0c9&pid=1-s2.0-S2452223624000750-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Green and Sustainable Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2452223624000750","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
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Abstract
Flow chemistry is now a key technology for synthetic chemistry, with the different operating windows available allowing new chemistry to be optimised and discovered. The related area of flow biocatalysis is also becoming increasingly recognised as an integral aspect of bioprocess optimisation, with modularisation and technology integration some of the key drivers for this. This minireview will discuss some recent examples where flow has substantially improved the sustainability of a bioprocess. We also reflect on the increase in analytics, how it is starting to impact bioprocess optimisation, and what the implications of this will be moving forward.
期刊介绍：
The Current Opinion journals address the challenge specialists face in keeping up with the expanding information in their fields. In Current Opinion in Green and Sustainable Chemistry, experts present views on recent advances in a clear and readable form. The journal also provides evaluations of the most noteworthy papers, annotated by experts, from the extensive pool of original publications in Green and Sustainable Chemistry.
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