Amorphous silicon detectors for proton beam monitoring in FLASH radiotherapy

IF 2.2 3区物理与天体物理 Q2 NUCLEAR SCIENCE & TECHNOLOGY Radiation Measurements Pub Date : 2024-07-08 DOI:10.1016/j.radmeas.2024.107230

Nicolas Wyrsch , Luca Antognini , Christophe Ballif , Saverio Braccini , Pierluigi Casolaro , Sylvain Dunand , Alexander Gottstein , Matt Large , Isidre Mateu , Jonathan Thomet

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Abstract

Ultra-high dose rate radiation therapy (FLASH) based on proton irradiation is of major interest for cancer treatments but creates new challenges for dose monitoring. Amorphous hydrogenated silicon is known to be one of the most radiation-hard semiconductors. In this study, detectors based on this material are investigated at proton dose rates similar to or exceeding those required for FLASH therapy. Tested detectors comprise two different types of contacts, two different thicknesses deposited either on glass or on polyimide substrates. All detectors exhibit excellent linear behaviour as a function of dose rate up to a value of 20 kGy/s. Linearity is achieved independently of the depletion condition of the device and remarkably in passive (unbiased) conditions. The degradation of the performance as a function of the dose rate and its recovery are also discussed.

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用于 FLASH 放射疗法质子束监测的非晶硅探测器

基于质子辐照的超高剂量率放射治疗（FLASH）对癌症治疗具有重大意义，但也给剂量监测带来了新的挑战。众所周知，非晶氢化硅是最耐受辐射的半导体之一。在这项研究中，我们对基于这种材料的探测器进行了研究，其质子剂量率类似或超过了 FLASH 治疗所需的剂量率。测试的探测器包括两种不同类型的触点，两种不同厚度的触点，分别沉积在玻璃或聚酰亚胺基底上。所有探测器都表现出与剂量率（最高达 20 kGy/s）呈良好的线性关系。线性度的实现与设备的耗尽条件无关，在被动（无偏差）条件下效果显著。此外，还讨论了性能随剂量率的下降及其恢复情况。

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来源期刊

Radiation Measurements 工程技术-核科学技术

CiteScore

4.10

自引率

20.00%

发文量

116

审稿时长

48 days

期刊介绍： The journal seeks to publish papers that present advances in the following areas: spontaneous and stimulated luminescence (including scintillating materials, thermoluminescence, and optically stimulated luminescence); electron spin resonance of natural and synthetic materials; the physics, design and performance of radiation measurements (including computational modelling such as electronic transport simulations); the novel basic aspects of radiation measurement in medical physics. Studies of energy-transfer phenomena, track physics and microdosimetry are also of interest to the journal. Applications relevant to the journal, particularly where they present novel detection techniques, novel analytical approaches or novel materials, include: personal dosimetry (including dosimetric quantities, active/electronic and passive monitoring techniques for photon, neutron and charged-particle exposures); environmental dosimetry (including methodological advances and predictive models related to radon, but generally excluding local survey results of radon where the main aim is to establish the radiation risk to populations); cosmic and high-energy radiation measurements (including dosimetry, space radiation effects, and single event upsets); dosimetry-based archaeological and Quaternary dating; dosimetry-based approaches to thermochronometry; accident and retrospective dosimetry (including activation detectors), and dosimetry and measurements related to medical applications.