Linking the brain to recovery after myocardial infarction

IF 9.4 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Nature cardiovascular research Pub Date : 2024-07-12 DOI:10.1038/s44161-024-00497-x
Dylan C. Sarver, Aldons J. Lusis
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Abstract

Myocardial infarction can damage the heart muscle and lead to heart failure. Research on recovery typically focuses on infiltrating immune cells, damaged cardiomyocytes, over-stimulated fibroblasts and changes in vasculature. Haykin et al. now describe a multi-organ circuit linking these entities, including the brain and liver, in the repair process.

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将大脑与心肌梗塞后的恢复联系起来
心肌梗塞会损伤心肌并导致心力衰竭。有关恢复的研究通常侧重于浸润的免疫细胞、受损的心肌细胞、过度刺激的成纤维细胞和血管的变化。海金等人现在描述了在修复过程中连接这些实体(包括大脑和肝脏)的多器官回路。
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