{"title":"Transition‐Metal Catalyzed Enantioselective Aziridination Reaction: Recent Development in Catalysis and Future Perspectives","authors":"Gui-Lin Hao, Juanjuan Wang, Shu-Bin Mou, Mu-Peng Luo, Qiaoqiao Teng, Shou-Guo Wang","doi":"10.1002/cctc.202400791","DOIUrl":null,"url":null,"abstract":"Chiral aziridines are important motifs in natural products and biologically significant compounds, as well as one of the most valuable and versatile building blocks for the construction of diverse chiral functionalized amines. Because of the importance of chiral aziridines, various novel transition‐metal‐based catalytic systems and synthetic strategies have been established to investigate the highly effective and enantioselective aziridination process. This review outlined the recent significant advances made in the transition‐metal catalyzed enantioselective aziridination reactions, as well as the challenges and potential of the field at the current stage.","PeriodicalId":141,"journal":{"name":"ChemCatChem","volume":null,"pages":null},"PeriodicalIF":3.8000,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ChemCatChem","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1002/cctc.202400791","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Chiral aziridines are important motifs in natural products and biologically significant compounds, as well as one of the most valuable and versatile building blocks for the construction of diverse chiral functionalized amines. Because of the importance of chiral aziridines, various novel transition‐metal‐based catalytic systems and synthetic strategies have been established to investigate the highly effective and enantioselective aziridination process. This review outlined the recent significant advances made in the transition‐metal catalyzed enantioselective aziridination reactions, as well as the challenges and potential of the field at the current stage.
期刊介绍：
With an impact factor of 4.495 (2018), ChemCatChem is one of the premier journals in the field of catalysis. The journal provides primary research papers and critical secondary information on heterogeneous, homogeneous and bio- and nanocatalysis. The journal is well placed to strengthen cross-communication within between these communities. Its authors and readers come from academia, the chemical industry, and government laboratories across the world. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and is supported by the German Catalysis Society.
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