ChemCatChem最新文献

The Front Cover illustrates the generation of carbon radicals through the cleavage of carbon–sulfur bonds in alkyl benzothiazolyl sulfides by using Hantzsch ester. In their Research Article (DOI: 10.1002/cctc.202401427), T. Sengoku and co-workers report how they successfully achieved this radical generation under blue light by two methods: one employing caesium carbonate and the other combining 4DPAIPN with potassium carbonate. This approach provides a more direct synthetic route by avoiding the preparation of sulfone intermediates and demonstrates its utility in the synthesis of C-glycoside.

The Cover Feature shows the creation of carbon dots (CDs) with multivalent amine ligands represented by the glowing core with a hairy surface. These CDs catalyze the denitrosylation of S-nitrosothiols, enabling the controlled release of nitric oxide (NO) under physiological conditions. Nucleophilic reaction by the primary amine groups drives the NO generation. Integration of these active CDs into a hydrogel-based prototissue allows biological NO-releasing platforms with future biomedical applications to be constructed. More information can be found in the Research Article by S. Rana and co-workers (DOI: 10.1002/cctc.202401338).

The Front Cover highlights an innovative approach for incorporating lipase into deep eutectic solvents (DES) with silica as a mediator, forming an efficient biocatalytic system. The dynamic interface illustrates the seamless interaction between the biocatalyst and the DES, emphasizing its transformative role in ester synthesis. In their Research Article (DOI: 10.1002/cctc.202401393), A. Chrobok and co-workers investigate how silica facilitates enzyme integration, enhancing stability and activity to enable more sustainable and effective biocatalysis. Art by the team of INMYWORK Studio.

The Front Cover shows the synergistic effects of a decoy molecule and directed evolution in cytochrome P450BM3. The developed P450BM3 mutant exhibits significantly high catalytic activity toward the hydroxylation of benzene, toluene, and propane in the presence of a natural decoy molecule, N-decanoyl homoserine lactone. This research demonstrates that exploring the vast combinations of mutations and decoy molecules—like a “space probe”—can lead to exceptional functional outcomes. More information can be found in the Research Article by S. Ariyasu, H. Sugimoto, O. Shoji and co-workers (DOI: 10.1002/cctc.202401641).

The Cover Feature shows the exploration of innovative routes in the late-stage oxidation of terpenoids by combining chemical and enzymatic catalysis to achieve the first successful oxyfunctionalization of complex tricyclic and macrocyclic terpenoids. Novel oxiranes and hemiacetals were formed through epoxidation and hydroxylation catalyzed by unspecific peroxygenases (UPOs), expanding the terpenome and unlocking pathways for bioactive compounds like flavors, fragrances, and APIs. More information can be found in the Research Article by A. Kirschning, S. Kara and co-workers (DOI: 10.1002/cctc.202401414). Dr. Hanna Grimm is acknowledged for the cover design.

The Front Cover illustrates the process of photocatalytic nitrogen fixation by 2D materials. Two-dimensional materials efficiently capture light to drive the generation of electron–hole pairs, which induce the conversion of nitrogen into ammonia. The image highlights 2D layered structure immersed in water, interacting with reactive molecules. This strategy offers promising advances in artificial nitrogen fixation under mild conditions. More information can be found in the Review by Y.-J. Zeng and co-workers (DOI: 10.1002/cctc.202401355).

The Cover Feature refers to an in-depth discussion about Pt-containing catalysts or the corresponding reaction mechanism over these catalysts, presented in their Review article by Magdalena Jabłońska and Adrián Osorio Hernández. The authors address the dispersion of Pt particles, as the main point including the catalytic properties of catalysts in H₂-SCR-DeNO_x over exclusively recent relevant literature reports on the subject. Additionally, as solar and wind energy sources continue to advance, the availability of green hydrogen is expected to increase in the future, making this review even more timely. More information can be found in the Review by Magdalena Jabłońska and Adrián Osorio Hernández (DOI: 10.1002/cctc.202400977).

The Front Cover highlights Pd nanoparticles enhancing the reverse water-gas shift (RWGS) activity of Mn-substituted SrTiO₃ (SrTi_0.8Mn_0.2O₃) as a co-catalyst in the Mars-van Krevelen (MvK)-type mechanism with a partial contribution from the Langmuir–Hinshelwood (L–H) mechanism. The MvK mechanism, which leverages lattice oxygen as the oxidant and oxygen vacancies as reductants, offers an alternative catalytic strategy for the selective RWGS reaction. The study by Shimpei Naniwa, Kentaro Teramura, and co-workers underscores the effectiveness of combining metal and MvK-type catalysts to enhance the efficiency of the RWGS reaction. More information can be found in the Research Article by Shimpei Naniwa, Kentaro Teramura, and co-workers (DOI: 10.1002/cctc.202400871).

Hydrogenation of nitro, carbonyl groups, and unsaturated bonds of sulfur-containing compounds over supported metal catalysts is a green process in the production of building blocks of bioactive natural compounds, drugs, pesticides, and so forth, but it is a challenging task due to the strong coordination and complexation of the lone pair electrons in sulfur atom with active sites in catalyst, leading to dramatically reduced activity. Previous studies emphasize the sulfur-resistant properties of catalysts in the hydrogenation of industrial feedstocks, but the direct hydrogenation of sulfur-containing compounds has received limited attention. In this concept, recent advances in the hydrogenation of sulfur-containing compounds were reviewed, including the strategies to improve the resistance of supported metal catalysts to sulfur poisoning. Finally, we give future perspectives on the development of efficient catalysts for the hydrogenation of sulfur-containing compounds, and key factors influencing the hydrogen dissociation and migration in the presence of sulfur atoms are highlighted.