Anticoagulant in Acute Ischemic Stroke with Atrial Fibrillation: A Narrative Review

S. J. B. Sayeed, Md Moniruzzaman, Md Mujibur Rahman
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Abstract

Embolic stroke due to atrial fibrillation is often underdiagnosed and has high morbidity and mortality among ischemic stroke. So it is of paramount importance to start anticoagulants as early as possible to prevent further ischemic stroke. However, early initiation of anticoagulants has created much debate, major & minor bleeding related to it are a major concern, and resumption of anticoagulants after intracranial hemorrhage is still a gray zone. Here, we described a narrative review to shed some light on the major concerns such as the optimal time to start an anticoagulant, the best agent to administer, the resumption of anticoagulant after a hemorrhagic stroke, and anticoagulant therapy in chronic rheumatic heart disease (CRHD) based on the recently published article. J MEDICINE 2024; 25: 155-158
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心房颤动急性缺血性卒中的抗凝剂:叙述性综述
心房颤动导致的栓塞性中风往往诊断不足,在缺血性中风中具有较高的发病率和死亡率。因此,尽早开始使用抗凝药物以预防进一步的缺血性中风至关重要。然而,早期开始使用抗凝药物引起了许多争论,与此相关的大出血和小出血是一个主要问题,而颅内出血后恢复使用抗凝药物仍是一个灰色地带。在此,我们以最近发表的一篇文章为基础,对开始使用抗凝剂的最佳时间、最佳用药、出血性卒中后抗凝剂的恢复以及慢性风湿性心脏病(CRHD)的抗凝治疗等主要问题进行了叙述性综述。
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