Congenital Hypothyroidism in Adulthood: A Literature Review

Aparna Anil, Lekshmi R, Shaiju. S. Dharan
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Abstract

Congenital Hypothyroidism (CH), the common pediatric endocrine disorder, resulting from their impairment at tissue level. Congenital Hypothyroidism is a major concern now a days. Congenital Hypothyroidism is broadly classified into Primary hypothyroidism, secondary hypothyroidism, peripheral hypothyroidism, syndromic hypothyroidism and transient congenital hypothyroidism. Factors affecting congenital hypothyroidism include thyroid dyshormonogenesis, thyroid dysgenesis, resistance to Thyroid Hormone binding, defects in T3 and T4 release or genetic factors. Thyroid hormone is essential for normal brain development. Keywords: Congenital Hypothyroidism, Mental Retardation
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成年后的先天性甲状腺功能减退症:文献综述
先天性甲状腺功能减退症(CH)是一种常见的儿科内分泌疾病,是由于组织水平受损而导致的。如今,先天性甲状腺功能减退症已成为人们关注的焦点。先天性甲减大致可分为原发性甲减、继发性甲减、外周性甲减、综合征性甲减和一过性先天性甲减。影响先天性甲减的因素包括甲状腺激素生成障碍、甲状腺发育不良、甲状腺激素结合抵抗、T3和T4释放缺陷或遗传因素。甲状腺激素对大脑的正常发育至关重要:先天性甲状腺功能减退症 弱智
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