Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves
Catharine Chambers, Curtis L. Cooper, Abigail E. Kroch, S. Buchan, Claire E. Kendall, Jeffrey C. Kwong, Rahim Moideddin, Lena Nguyen, Gordon Arbess, Anita C. Benoit, Cecilia T. Costiniuk, Muluba Habanyama, N. Janjua, Marc-André Langlois, John McCullagh, Lawrence Mbuagbaw, N. Moqueet, Devan Nambiar, Sergio Rueda, H. Samji, Vanessa Tran, Sharon Walmsley, Aslam H Anis, A. Burchell
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Abstract
We found that rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and reverse transcriptase (RT)-PCR-confirmed infection were approximately 50% higher in a population-based cohort of people with HIV compared with a matched cohort of people without HIV during the Omicron era (2 January 2022 to 31 March 2023) in Ontario, Canada, after controlling for age, sex, residential census tract, and country of birth. Rates of coronavirus disease 2019 (COVID-19)-related hospitalization and/or death were more than double. Differences persisted independent of vaccination, healthcare access, and COVID-19 diagnosis.
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