CLINICAL PROFILE AND PREGNANCY OUTCOMES OF COVID POSITIVE PREGNANT WOMEN IN PHASE I ANDII INFECTION – A COMPARATIVE STUDY

Deepthi Ps, Sathiamma. Pk
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Abstract

Objectives: This study aims to assess the clinical features, the impact of coronavirus disease 2019 (COVID-19) infection during pregnancy, and the perinatal and obstetric outcomes in phases I and II. Methods: The current study was performed from January 2020 to August 2021 at the Government T D Medical College, Alappuzha. The pregnant women were registered instantly after each infected woman was known as per the inclusion and exclusion criteria. Demographic parameters, related comorbid disorders, intensive care unit admission, and complete treatment details of each woman were noted. Neonatal outcomes were documented. Results: There were 254 women in wave 1 and 164 women in wave 2 in the obstetric admissions. Still was seen in 3 cases (wave 1) and 2 cases (wave 2). In both phases, most pregnant women fall under the age category between 21 and 30. Multi-parity was found to be 50.8% in wave 1 women and 59.2% in wave 2 women were common in both waves. The period of gestation and obstetric comorbidities were found to be statistically significant with a p=0.007 (phase I) and 0.008 (phase II). Conclusion: Pregnancy-related COVID-19 infection may increase the threat of maternal death but has no influence on the morbidity and death of newborns. It is not possible to totally rule out the possibility of maternal-fetal transfer. Every wave of COVID-19 may have different characteristics and severity; therefore, our treatment plans must change. To confirm this transmission, more research or meta-analysis reports are needed.
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I 期和 II 期感染科维德阳性孕妇的临床概况和妊娠结局--一项比较研究
研究目的本研究旨在评估妊娠期冠状病毒病2019(COVID-19)感染的临床特征、影响以及第一和第二阶段的围产期和产科结果:本研究于 2020 年 1 月至 2021 年 8 月在阿拉普扎政府 T D 医学院进行。根据纳入和排除标准,在了解每位受感染妇女的情况后,立即对孕妇进行登记。记录了每位孕妇的人口统计学参数、相关合并症、重症监护室入院情况和完整的治疗细节。新生儿结局也记录在案:结果:产科收治的产妇中,第一波为 254 人,第二波为 164 人。有 3 例(第一阶段)和 2 例(第二阶段)出现死胎。在这两个阶段中,大多数孕妇的年龄在 21 岁至 30 岁之间。在第一阶段,50.8%的孕妇患有多胎妊娠,而在第二阶段,59.2%的孕妇患有多胎妊娠。妊娠期和产科合并症具有统计学意义,P=0.007(第一阶段)和 0.008(第二阶段):与妊娠相关的 COVID-19 感染可能会增加产妇死亡的威胁,但对新生儿的发病率和死亡率没有影响。不能完全排除母婴传播的可能性。COVID-19 的每一波感染都可能有不同的特征和严重程度,因此我们的治疗方案必须改变。要证实这种传播,还需要更多的研究或荟萃分析报告。
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