CLINICAL PROFILE, RISK FACTORS, AND PULMONARY FUNCTION TESTS IN PATIENTS OF OBSTRUCTIVE SLEEP APNEA

GUGULOTH MANOSRI SOWMYA, A MOUNIKA, B BHANU REKHA
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Abstract

Objectives: The aim of this study was to analyze clinical profile, risk factors, and pulmonary function test (PFT) in patients with obstructive sleep apnea (OSA). Methods: This was a prospective study undertaken in the department of pulmonary medicine of a tertiary care medical institute in which adult patients OSA were included on the basis of a predefined inclusion and exclusion criteria. Demographic details of patients were noted. Gender distribution, age distribution, clinical profile, and risk factors were studied. Severity of OSA was assessed by apnea hypopnea index (AHI). PFTs were done in all the cases. Results: Out of 60 studied cases, there were 39 (65.00%) males and 21 (35.00%) females with a M: F ratio of 1: 0.53. The mean age of the studied cases was 51.58±11.14 years. The most common risk factor present in studied cases was increased neck circumference. Severity of OSA, as determined by AHI, was found to be mild, moderate, and severe in 34 (56.67%), 20 (33.33%), and 6 (10.00%) patients, respectively. Snoring that was bothersome to others was the most common presenting complaints in studied cases and was found in 52 (86.67%) cases. PFT was normal in 23 (38.33%) patients whereas obstructive as well as restrictive features were seen in 16 (26.67%) and 14 (23.33%) patients, respectively. Conclusion: PFTs should be included during workup of patients with OSA and obstructive lung disease may coexist and cause an increase in mortality.
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阻塞性睡眠呼吸暂停患者的临床概况、风险因素和肺功能测试
研究目的本研究旨在分析阻塞性睡眠呼吸暂停(OSA)患者的临床概况、风险因素和肺功能测试(PFT):这是一项在一家三级医疗机构肺内科进行的前瞻性研究,根据预先确定的纳入和排除标准纳入了 OSA 成年患者。研究记录了患者的详细人口统计学资料。对性别分布、年龄分布、临床特征和风险因素进行了研究。通过呼吸暂停低通气指数(AHI)评估 OSA 的严重程度。所有病例均进行了肺功能检查:在 60 例研究病例中,男性 39 例(65.00%),女性 21 例(35.00%),男女比例为 1:0.53。研究病例的平均年龄为(51.58±11.14)岁。研究病例中最常见的危险因素是颈围增大。根据 AHI 确定,34 例(56.67%)、20 例(33.33%)和 6 例(10.00%)患者的 OSA 严重程度分别为轻度、中度和重度。在研究病例中,52 例(86.67%)患者最常见的主诉是鼾声扰人。23例(38.33%)患者的肺活量正常,而16例(26.67%)和14例(23.33%)患者的肺活量分别出现阻塞性和局限性特征:结论:在对 OSA 患者进行检查时,应将 PFT 包括在内,阻塞性肺部疾病可能同时存在,并导致死亡率上升。
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